北京中医药大学学报2026，Vol.49Issue(2)：245-250,6.DOI:10.3969/j.issn.1006-2157.2026.02.010
基于"伏邪"理论探讨类风湿关节炎的态靶辨治
Exploration of the syndrome-target differentiation and treatment of rheumatoid arthritis based on the theory of"latent pathogens"
摘要
Abstract
Rheumatoid arthritis(RA)is an autoimmune inflammatory disease that can be categorized under the traditional Chinese medicine(TCM)concept of"Bi syndrome."It causes joint pain,bone destruction,and extrasynovial multisystem damage,posing severe threats to patients' health.Based on the disease's onset characteristics,we illustrate the theory of"latent pathogens"combined with the syndrome-target differentiation and treatment concept,divide the disease into four stages:emergence,expansion,latency,and chronicity.This approach aligns with the evolution of pathogenesis,identify the challenge of recurrent episodes and difficulty in achieving a cure,and provide new ideas for the holistic differentation and treatment of RA,forming a general principle of strengthening the vital qi,dispelling cold and dampness,clearing blood stasis and heat,and unblocking meridians for RA treatment.In terms of disease manifestations,five states of"deficiency,cold,dampness,heat,and stasis"are summarized.With Guizhi Shaoyao Zhimu Decoction as the main prescription targeting the disease,staging-based modification as the foundation,adjustments needed to be made according to the patient's most prominent state,and incorporation of target drugs aimed at symptoms,physicochemical indicator,and imaging targets.RA treatment system based on staged differentiation and targeted therapy is constructed to improve the clinical effecacy.关键词
类风湿关节炎/伏邪/分期论治/态靶辨治Key words
rheumatoid arthritis/latent pathogens/staged treatment/syndrome-target differentiation and treatment分类
医药卫生引用本文复制引用
包诗航,汪悦..基于"伏邪"理论探讨类风湿关节炎的态靶辨治[J].北京中医药大学学报,2026,49(2):245-250,6.基金项目
国家自然科学基金项目(No.81973769) （No.81973769）
江苏省中医药科技发展计划项目(No.QN202209) National Natural Science Foundation of China(No.81973769) （No.QN202209）
