临床口腔医学杂志2026，Vol.42Issue(2)：81-85,5.DOI:10.3969/j.issn.1003-1634.2026.02.005
CT与MRI诊断下颌牙龈鳞状细胞癌下颌骨侵犯的对比研究
Comparison of CT and MRI for diagnosing mandibular invasion in gingival squamous cell carcinoma
摘要
Abstract
Objective:To evaluate the diagnostic accuracy of contrast-enhanced computed tomography(CT)and magnetic resonance imaging(MRI)in assessing bone invasion in patients with mandibular gingival squamous cell carcinoma(GSCC),and to explore the clinicopathological factors influencing their diagnostic reliability.Methods:Patients with man-dibular gingival carcinoma treated at the Stomatological Hospital of the First Affiliated Hospital of Xinjiang Medical University from June 2023 to July 2025 were enrolled.Preoperative CT and MRI scans were evaluated for the presence of mandibular bone invasion.Using pathological findings as the gold standard,the sensitivity,specificity,positive predictive value(PPV),negative predictive value(NPV),and overall diagnostic accuracy of CT and MRI in detecting mandibular involvement were analyzed.The influence of clinicopathological features on the diagnostic accuracy of both imaging modalities was also investi-gated.Results:This study analyzed 40 patients with mandibular GSCC(18 with pathologically confirmed bone invasion and 22 without).Comparison of the diagnostic performance showed that MRI had higher diagnostic accuracy(77.5％vs.72.5％),sensitivity(88.9％vs.83.3％),specificity(68.2％vs.63.6％),PPV(69.6％vs.65.2％),and NPV(88.2％vs.82.4％)than CT.However,both imaging techniques demonstrated moderate agreement with pathological results(Kappa:MRI=0.557,CT=0.458),with no statistically significant difference between CT and MRI(P>0.05).McNemar's test indicated no signif-icant difference in diagnostic outcomes between CT and MRI(P>0.05).Additionally,MRI findings were significantly associ-ated with primary tumor location(anterior/posterior region)and higher T stage(P<0.05),while no such correlation was ob-served with CT.Conclusion:MRI and CT exhibit comparable efficacy in diagnosing bone invasion in mandibular GSCC.How-ever,MRI findings show significant correlations with tumor location and T stage,providing superior clinical relevance and ad-ditional reference for preoperative evaluation.关键词
下颌牙龈鳞状细胞癌/骨侵犯/磁共振成像/计算机断层扫描/诊断准确性Key words
Mandibular gingival squamous cell carcinoma/Bone invasion/Magnetic resonance imaging(MRI)/Computed tomography(CT)/Diagnostic accuracy分类
医药卫生引用本文复制引用
吾塔别克·哈布力,吴旭彬,买买提吐逊·吐尔地..CT与MRI诊断下颌牙龈鳞状细胞癌下颌骨侵犯的对比研究[J].临床口腔医学杂志,2026,42(2):81-85,5.基金项目
国家自然科学基金项目(82360198) （82360198）
