中草药2026，Vol.57Issue(5)：1597-1602,6.DOI:10.7501/j.issn.0253-2670.2026.05.001
赤水金钗石斛中2个新化学成分
Two new compounds from Chishui Dendrobium nobile
摘要
Abstract
Objective Study on the chemical components of Chishui Dendrobium nobile(Orchidaceae).Methods A systematic chemical study was conducted on the n-butanol fraction of the 95%ethanol extract of Chishui D.nobile using methods and techniques such as silica gel,Toyopearl HW-40C,and semi-preparative liquid chromatography,with structural identification carried out through HRESIMS,NMR,IR,UV,and other spectroscopic methods.Results A total of six compounds were isolated and identified as 6,7-dimethyl-1-[(2S,3R,4R)-2,3,5-trihydroxy-4-O-β-D-glucopyranosyl]-1,4-dihydroquinoxaline-2,3-dione(1),2-phenylethyl 3-O-β-D-glucopyranosyl-β-D-glucopyranoside(2),diospyrososide(3),benzyl-β-D-glucoside(4),icariside D2(5),2-methoxyphenyl-β-D-glucopyranoside(6).Conclusion Compound 1 was identified as a new alkaloid,named dendronobiline A1,while compound 2 was identified as a new phenylethanoid glycoside,named dendronobiside A1.Compounds 3-6 are isolated from the plant for the first time.关键词
金钗石斛/生物碱/糖苷/金钗石斛碱A1/金钗石斛苷A1/苄基-β-D-葡萄糖苷/淫羊藿次苷D2Key words
Dendrobium nobile Lindl./alkaloid/glycoside/dendronobiline A1/dendronobiside A1/benzyl-β-D-glucoside/icariside D2分类
医药卫生引用本文复制引用
张俊阳,杨梦,郝志友,王小兰,刘志霞,马旭东,肖超远,郑晓珂,冯卫生..赤水金钗石斛中2个新化学成分[J].中草药,2026,57(5):1597-1602,6.基金项目
中央引导地方科技发展专项资金([2016]149) （[2016]149）
河南省科技攻关项目(212102311091) （212102311091）
