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放射性口腔黏膜炎的疾病管理模式

朱伟文 范媛

中国实用口腔科杂志2026,Vol.19Issue(1):27-31,5.
中国实用口腔科杂志2026,Vol.19Issue(1):27-31,5.DOI:10.19538/j.kq.2026.01.004

放射性口腔黏膜炎的疾病管理模式

Disease management model of radiation-induced oral mucositis

朱伟文 1范媛1

作者信息

  • 1. 南京医科大学附属口腔医院黏膜病科,口腔疾病研究与防治国家及重点实验室培育单位(南京医科大学),江苏省口腔转化医学工程研究中心(南京医科大学),江苏南京 210029
  • 折叠

摘要

Abstract

Radiation-induced oral mucositis(RIOM)is a common toxic reaction that may limit continuous treatment in head-and-neck radiotherapy and chemoradiotherapy.It typi-cally presents with oral mucosal erythema,erosions or ulcers,and severe pain,often accompanied by malnutrition and infec-tion.Based on current national and international guidelines and the Chinese group standards,this paper puts forward an integrated,full-cycle management model,including:systemat-ic oral evaluation,risk stratification,and health education be-fore radiotherapy;standardized oral hygiene management sup-ported by appropriate local or systemic prophylactic measures through the course of treatment;severity-based therapeutic strategies that combine analgesia,anti-infection,nutritional support,and pro-healing interventions during treatment,with radiotherapy plan optimized if necessary;regular follow-up combined with patient-reported outcome measures(PROMs)and quality improvement(QI)indicators to form a closed man-agement loop.This model is designed to reduce the incidence of severe RIOM and treatment interruptions,accelerate heal-ing,and improve patients' quality of life.

关键词

放射性口腔黏膜炎/风险评估/临床分级/临床质量改进

Key words

radiation-induced oral mucositis/risk assess-ment/clinical grading/clinical quality improvement

分类

医药卫生

引用本文复制引用

朱伟文,范媛..放射性口腔黏膜炎的疾病管理模式[J].中国实用口腔科杂志,2026,19(1):27-31,5.

基金项目

江苏省科技厅重点研发项目(社会发展)专项基金(BE2021723) (社会发展)

江苏省卫健委面上项目(H2023149) (H2023149)

中国实用口腔科杂志

1674-1595

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