中国猪业2026，Vol.21Issue(1)：40-55,16.DOI:10.16174/j.issn.1673-4645.2026.01.006
细菌胞外囊泡在防控断奶仔猪腹泻和肠炎中的作用和潜力
The role and potential of bacterial extracellular vesicles in preventing and controlling diarrhea and intestinal inflammation in weaned piglets
摘要
Abstract
Bacterial extracellular vesicles(BEVs)are nano-scale membrane-enclosed structures actively secreted by all bac-teria,with a diameter ranging from 20～400 nm.They carry various bioactive molecules such as proteins,nucleic acids,and lipids,and play a key role in bacterial physiological activities and host interactions.With the integration of veterinary medicine and nanobiology,research on BEVs in the field of swine disease prevention and control is increasingly in-depth.This article systematically reviewed the biological characteristics of bacterial extracellular vesicles,compared the functional differences between BEVs derived from Gram-positive and Gram-negative bacteria,analyzed their composition and interaction mecha-nisms with the host,emphatically elaborated on the application practices and mechanisms of action of BEVs in postweaning diarrhea in piglets,further looked forward to their industrial application potential,aiming to provide a theoretical reference for the development of precise prevention and control technologies for postweaning diarrhea in piglets.关键词
细菌胞外囊泡/益生菌/肠道菌群/腹泻/猪/免疫调节Key words
bacterial extracellular vesicles/probiotic/gut microbiota/diarrhea/pig/immunomodulation分类
农业科技引用本文复制引用
罗瑶瑶,施晨辰,张亦弛,王九峰,杨贵燕..细菌胞外囊泡在防控断奶仔猪腹泻和肠炎中的作用和潜力[J].中国猪业,2026,21(1):40-55,16.基金项目
国家自然科学基金项目(32573438) （32573438）
