东华大学学报（英文版）2026，Vol.43Issue(1)：1-9,9.DOI:10.19884/j.1672-5220.202504002
光诱导电子转移驱动的α-酮酯还原偶联高效构建碳-碳键
Photoinduced Electron Transfer-Driven Reductive Coupling of α-Keto Esters for Efficient Carbon-Carbon Bond Construction
摘要
Abstract
Catalytic reduction reactions using isopropanol(IPA)as a transfer hydrogenating agent are gaining significant attention due to the low cost and large-scale production of IPA.Traditional methods for carbon-carbon(C—C)bond construction often rely on expensive and scarce transition metal catalysts,raising concerns about sustainability and environmental impact.To address these challenges,we develop a bifunctional photocatalyst,phloroglucinol carbon quantum dot(PG-CQD).It facilitates catalytic transfer hydrogenation(CTH)with IPA as the hydrogen donor.PG-CQDs exhibit both dehydrogenation and reduction activities,enabling the formation of vicinal diols under mild conditions with visible light irradiation.We propose a CTH mechanism that has been successfully validated through experiments.The catalytic system demonstrates remarkable versatility,enabling the synthesis of various vicinal diols from diverse α-keto ester substrates with good or excellent yields.These findings offer a sustainable synthetic strategy that aligns with green chemistry principles and establish a promising pathway for the development of environmentally benign and energy-efficient organic transformations.关键词
碳-碳(C—C)键/还原偶联/催化转移氢化/可见光/碳量子点/异丙醇Key words
carbon-carbon(C—C)bond/reductive coupling/catalytic transfer hydrogenation(CTH)/visible light/carbon quantum dot(CQD)/isopropanol(IPA)分类
化学化工引用本文复制引用
陈迪,王乐..光诱导电子转移驱动的α-酮酯还原偶联高效构建碳-碳键[J].东华大学学报（英文版）,2026,43(1):1-9,9.基金项目
National Natural Science Foundation of China(Nos.21902023 and 21901252) （Nos.21902023 and 21901252）
Shanghai Pujiang Program,China(No.19 PJ1400300) （No.19 PJ1400300）
Professor of Special Appointment(Eastern Scholar),China （Eastern Scholar）
Shanghai Institutions of Higher Education Fundamental Research Funds for the Central Universities,China(No.0900000155) （No.0900000155）
