口腔疾病防治2026，Vol.34Issue(3)：292-301,10.DOI:10.12016/j.issn.2096-1456.202550320
磨牙-切牙釉质矿化不全诊疗策略研究进展
Advancements in the diagnosis and treatment strategies for molar-incisor hypomineralization
摘要
Abstract
Molar-incisor hypomineralization(MIH)is a developmental defect of enamel that is characterized primar-ily by abnormal enamel mineralization affecting the first permanent molars and permanent incisors.Due to insufficient mineralization,teeth affected by MIH are prone to post-eruptive breakdown and caries,potentially leading to sequelae such as tooth sensitivity and occlusal problems.The diagnosis of MIH is primarily based on relevant perinatal and infan-tile medical history,the characteristic distribution of affected teeth,and the morphological features of the enamel de-fects.Based on the extent and severity of the enamel defect,MIH is classified as mild or severe.Diagnosis and treat-ment strategies emphasize early screening,diagnosis,and intervention,prioritizing prevention,providing symptomatic care,and implementing regular recall assessments.Mild MIH predominantly manifests as demineralized enamel opaci-ties or discoloration,typically without significant enamel breakdown.Treatment focuses on caries prevention and aes-thetic restoration,employing techniques such as remineralization,micro-abrasion,resin infiltration,bleaching,fluoride application,and fissure sealants.Severe MIH typically presents with extensive enamel opacities accompanied by sub-stantial enamel breakdown and may be complicated by caries and tooth sensitivity.Management primarily involves re-storing the structural defects or,for teeth that cannot be preserved,extraction followed by orthodontic treatment.Com-prehensive management often requires a multimodal approach integrating various therapeutic modalities to restore both the function and aesthetics of the affected teeth and overall dentition.This article provides a review of advancements in diagnosis and the treatment strategies for MIH,offering a reference for clinical practice.关键词
磨牙-切牙釉质矿化不全/牙釉质发育缺陷/第一恒磨牙/切牙/诊疗策略/龋病/牙体缺损/口腔健康Key words
molar-incisor hypomineralization/developmental defects of enamel/first permanent molar/inci-sor/diagnosis and treatment strategies/dental caries/dental defects/oral health分类
医药卫生引用本文复制引用
赵芳,王欣,黄进伟,刘景平,徐赫..磨牙-切牙釉质矿化不全诊疗策略研究进展[J].口腔疾病防治,2026,34(3):292-301,10.基金项目
北京市自然科学基金面上项目(7242172) （7242172）
北京大学口腔医院临床新技术新疗法项目(PKUSSNCT-25A13) This study was supported by the grants from Beijing Natural Science Foundation General Program(No.7242172) （PKUSSNCT-25A13）
Pro-gram for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology(No.PKUSSNCT-25A13). （No.PKUSSNCT-25A13）
