分析化学2026，Vol.54Issue(2)：225-231,7.DOI:10.19756/j.issn.0253-3820.251342
基于原位生成荧光聚合物纳米颗粒的草甘膦检测方法
Detection of Glyphosate Based on In Situ Formation of Fluorescent Polymer Nanoparticles
摘要
Abstract
A convenient and sensitive fluorescent sensor was successfully constructed for quantitative determination of glyphosate based on the in situ formation of fluorescent polymer nanoparticles(FPNPs)through Cu2+-triggered polymerization and the strong coordination interaction between Cu2+and glyphosate.Cu2+initiated the rapid copolymerization of dopamine(DA)andm-phenylenediamine(MPD),leading to the formation of FPNPs.However,when glyphosate was present,it coordinated with Cu2+,which significantly inhibited the formation of FPNPs,resulting in a decrease of the fluorescence intensity of the system.Consequently,fluorescent detection of glyphosate was achieved based on the Cu2+-DA-MPD system.Under the optimal experimental conditions,the method exhibited a linear detection range of 5–95 μmol/L with a limit of detection as low as 1.75 μmol/L(S/N=3).It also demonstrated high selectivity and excellent anti-interference capability.When this method was employed for detection of glyphosate in actual water samples,spiked recoveries between 97.8%and 103.3%were obtained,demonstrating its reliable practicality and substantial application potential in real sample analysis.Moreover,this method did not require the pre-preparation of fluorescent materials,offering a new idea for rapid detection of glyphosate.关键词
草甘膦/荧光/多巴胺/间苯二胺/聚合物纳米颗粒/原位生成Key words
Glyphosate/Fluorescence/Dopamine/m-Phenylenediamine/Polymer nanoparticles/In situ formation引用本文复制引用
杨昊东,董诗婧,马娅欣,马翱,逯一中,倪朋娟..基于原位生成荧光聚合物纳米颗粒的草甘膦检测方法[J].分析化学,2026,54(2):225-231,7.基金项目
国家自然科学基金项目(Nos.32202145,22172063)、山东省自然科学基金项目(No.ZR2022QB192)和山东省大学生创新创业训练计划项目(No.S202510427053)资助. Supported by the National Natural Science Foundation of China(Nos.32202145,22172063),the Natural Science Foundation of Shandong Province(No.ZR2022QB192)and the Shandong Provincial College Students' Innovation and Entrepreneurship Training Program(No.S202510427053). （Nos.32202145,22172063）
