广州中医药大学学报2026，Vol.43Issue(3)：567-572,6.DOI:10.13359/j.cnki.gzxbtcm.2026.03.003
基于病证相关探讨西北燥证对新疆地区肺结核的影响
Investigating the Influence of Northwest Dryness Syndrome on Pulmonary Tuberculosis in Xinjiang Based on Disease-Syndrome Correlation
摘要
Abstract
Objective Based on the correlation between the main syndrome of northwest dryness syndrome(NDS)and pulmonary tuberculosis(TB),this study preliminarily explores the impact of NDS,having the features of the arid regional climate and environment,on TB patients in Xinjiang.It aims to provide a scientific basis for employing auxiliary treatments,such as environmental optimization,to improve the quality of life for TB patients.Methods Using the main syndrome diagnostic scale for NDS,the prevalence of NDS was investigated in two groups:a case group consisting of TB patients(with a residence duration in Xinjiang≥3 years)attending the Aksu Infectious Disease Hospital,between January 2023 and December 2024,and a healthy control group(without TB or other related diseases,with a residence duration in Xinjiang≥3 years)selected from multiple communities in the Aksu region during the same period.The NDS syndrome scores were compared between the two groups.The clinical symptom scoring scale for TB was used to assess the western medical disease severity in TB patients.Based on the presence or absence of NDS,TB cases were divided into a TB-with-NDS group and a TB-without-NDS group,and their disease severity was compared.Traditional Chinese medicine(TCM)syndrome types were identified in TB patients using TCM syndrome differentiation methods,and the distribution differences of TCM syndrome types were compared between the TB-with-NDS and TB-without-NDS groups.Results(1)The prevalence of NDS in the TB case group was 47.00%(94/200),significantly higher than the 31.00%(62/200)in the healthy control group.The intergroup comparison(by chi-square test)showed a statistically significant difference(P＜0.01).(2)The NDS syndrome score in the TB case group was significantly higher than that in the healthy control group,with a statistically significant difference(P＜0.01).(3)The western medical disease severity score in the TB-with-NDS group was significantly higher than that in the TB-without-NDS group,with a statistically significant difference(P＜0.01).(4)The distribution of TCM syndrome types in both the TB-with-NDS group and TB-without-NDS group in descending order was lung yin deficiency syndrome,qi and yin deficiency syndrome,and yin and yang deficiency syndrome.The comparison of TCM syndrome distribution between the TB-with-NDS group and TB-without-NDS group showed a statistically significant difference(P＜0.01).Specifically,the proportion of patients with lung yin deficiency syndrome was lower in the TB-with-NDS group than in the TB-without-NDS group,while the proportions of patients with qi and yin deficiency syndrome and yin and yang deficiency syndrome were higher in the TB-with-NDS group than the TB-without-NDS group.Conclusion NDS is closely associated with the incidence of TB in the Xinjiang region,and is one of the key factors contributing to TB susceptibility in this population.关键词
肺结核/西北燥证/病证相关/新疆地区/中医证型/肺阴虚证/气阴两虚证/阴阳两虚证Key words
pulmonary tuberculosis/northwest dryness syndrome(NDS)/disease-syndrome correlation/Xinjiang region/TCM syndrome type/lung yin deficiency syndrome/qi and yin deficiency syndrome/yin and yang deficiency syndrome分类
医药卫生引用本文复制引用
梁丽丽,史红,玉苏甫·马木提,王家平,王萌,张庆..基于病证相关探讨西北燥证对新疆地区肺结核的影响[J].广州中医药大学学报,2026,43(3):567-572,6.基金项目
省部共建中亚高发病成因与防治国家重点实验室开放课题(编号:SKL-HIDCA-2022-XBZZ15) （编号:SKL-HIDCA-2022-XBZZ15）
