分析化学2026，Vol.54Issue(2)：251-261,11.DOI:10.19756/j.issn.0253-3820.251229
铕基金属有机框架材料修饰的聚多巴胺@MXene分子印迹电化学传感器检测磺胺二甲氧嘧啶
Europium Metal Organic Framework Modified Polydopamine@MXene Molecularly Imprinted Electrochemical Sensor for Detection of Sulfadimethoxine
摘要
Abstract
Sulfadimethoxine(SDM)is a broad-spectrum sulfonamide bacteriostatic agent widely used in aquaculture.However,improper usage leading to excessive residues poses potential threats to food safety and human health.Thus,developing rapid and sensitive detection methods for monitoring SDM in food is of great importance.In this study,an Eu-MOF-PDA@MXene composite material was prepared via an in-situ synthesis method.By modifying the surface layers with polydopamine(PDA)and europium metal organic framework(Eu-MOF),the oxidation and self-stacking of MXene were prevented,significantly enhancing its conductivity and structural stability.Based on this composite material and combined with molecular imprinting technique,a highly specific and sensitive MXene-based molecularly imprinted electrochemical sensor was constructed for rapid quantitative detection of SDM.Under the optimal detection conditions,the sensor exhibited an ultra-low detection limit(2.2 ng/L),a wide linear detection range(0.05–500 μg/L),as well as good selectivity,stability,and reproducibility.The sensor was successfully applied to detection of SDM in grass carp samples,with a detection time of only 3 min and spiked recoveries of 89.5%–91.1%,demonstrating good application potential.This study provided a rapid and simple method for determination of SDM residues in food,offering important technical guidance for food safety monitoring.关键词
分子印迹聚合物/金属有机框架/聚多巴胺@MXene/电化学传感器/磺胺二甲氧嘧啶Key words
Molecularly imprinted polymer/Metal organic framework/Polydopamin@MXene/Electrochemical sensor/Sulfadimethoxine引用本文复制引用
范梦晗,王沁仪,张丝瑶,李敏,李静,袁敏,徐斐..铕基金属有机框架材料修饰的聚多巴胺@MXene分子印迹电化学传感器检测磺胺二甲氧嘧啶[J].分析化学,2026,54(2):251-261,11.基金项目
国家重点研发计划项目(No.2022YFF1101102)资助. Supported by the National Key Research and Development Program of China(No.2022YFF1101102). （No.2022YFF1101102）
