广州中医药大学学报2026，Vol.43Issue(3)：787-794,8.DOI:10.13359/j.cnki.gzxbtcm.2026.03.034
基于数据挖掘探讨黄健玲治疗盆腔炎性疾病的用药规律
Exploration of Medication Patterns in Huang Jianling's Treatment of Pelvic Inflammatory Disease Based on Data Mining
摘要
Abstract
Objective To explore the medication characteristics and prescription patterns of Professor Huang Jianling in treating pelvic inflammatory disease(PID).Methods Medical records of first-visit patients diagnosed with PID at Professor Huang Jianling's outpatient clinic in Guangdong Provincial Hospital of Chinese Medicine between October 2021 and September 2024,who showed effective response to oral Chinese medicine treatment,were collected.Based on the Traditional Chinese Medicine Inheritance Support System(V2.5),statistics were performed on the occurrence frequency of symptoms,syndrome types and herbs,as well as the distribution of four natures,five flavors,meridian tropism,and efficacy categories of the herbs.Association rule analysis and cluster analysis were employed to excavate her medication patterns and clinical experience.Results A total of 217 medical records was included,involving 63 symptoms.The top 5 frequently-seen main symptoms were lower abdominal pain,dysmenorrhea,insomnia,profuse leukorrhea,and infertility.Nineteen syndrome type were identified,and the most common type were spleen deficiency with dampness accumulation syndrome,damp-heat and blood stasis obstruction syndrome,and kidney deficiency with blood stasis syndrome.The 243 Chinese medicine prescriptions involved 78 herbs,with a cumulative occurrence frequency of 2 856 times.Twenty high-frequency herbs were used 50 times or more.The most frequently-used herbs were Ilex Pubescens Radix,Salviae Miltiorrhizae Radix et Rhizoma,Paeoniae Radix Rubra,Atractylodis Macrocephalae Rhizoma,Poria,Angelicae Sinensis Radix,Taxilli Herba,Patriniae Herba,Curcumae Radix,Cyperi Rhizoma,and Liquidambaris Fructus.The herbs used were mainly neutral in nature,followed by cold and warm properties.The primary flavor was bitter,followed by sweet and pungent flavors.Most of the herbs had the meridian tropism of the liver,spleen,and kidney meridians.The herbal efficacies were classified into 15 categories,and tonifying herbs and blood-activating and stasis-resolving herbs ranked ahead of other herbs.Association rule analysis revealed that Ilex Pubescens Radix,Salviae Miltiorrhizae Radix et Rhizoma,Paeoniae Radix Rubra,Atractylodis Macrocephalae Rhizoma,Poria,Angelicae Sinensis Radix,and Taxilli Herba constituted the core herbal combination for treating PID.For the main symptom of lower abdominal pain,Cyperi Rhizoma and Patriniae Herba were typically added;for dysmenorrhea,Cyperi Rhizoma,Aucklandiae Radix,Liquidambaris Fructus and Patriniae Herba were usually added;for insomnia,Curcumae Radix was usually added;for profuse leukorrhea,Cyperi Rhizoma,Aucklandiae Radix,Patriniae Herba,Curcumae Radix and Dioscoreae Hypoglaucae Rhizoma were often added;for infertility,Liquidambaris Fructus,Cudraniae Radix and Cuscutae Semen were frequently added.Cluster analysis yielded 4 potential new formula combinations.Conclusion For the syndrome differentiation and treatment of PID,Professor Huang Jianling holds a view that PID has a complex pathogenesis of deficiency and excess,characterized by the pathogenic excess of dampness,heat and stasis,and accompanied by spleen-kidney qi deficiency.The treatment of PID should be focused on resolving stasis and unblocking collaterals,clearing heat and draining dampness,while concurrently fortifying the spleen and tonifying the kidney.关键词
盆腔炎性疾病/脾虚湿蕴/湿热瘀阻/肾虚血瘀/毛冬青/丹参/赤芍/白术/茯苓/当归/桑寄生/数据挖掘/黄健玲分类
医药卫生引用本文复制引用
张嘉晔,王军飞,陈敏红..基于数据挖掘探讨黄健玲治疗盆腔炎性疾病的用药规律[J].广州中医药大学学报,2026,43(3):787-794,8.基金项目
广东省中医药局中医药科研项目(编号:20254072) （编号:20254072）
全国名老中医药专家黄健玲名医传承工作室建设项目(国中医药人教函[2022]75号) （国中医药人教函[2022]75号）
广州市科技计划项目(编号:2023A04J0463) （编号:2023A04J0463）
