国际妇产科学杂志2026，Vol.53Issue(1)：27-32,6.DOI:10.12280/gjfckx.20250680
以阴道大出血为首发症状的宫颈上皮样滋养细胞肿瘤成功治疗一例
Cervical Epithelioid Trophoblastic Tumor Presenting with Vaginal Massive Hemorrhage as the Initial Symptom:A Successfully Managed Case Report
香惠华 1吴珮君 1何欣怡 1叶飞 1罗新 1林伟钊 1舒珊荣1
作者信息
- 1. 510632 广州,暨南大学附属第一医院妇科
- 折叠
摘要
Abstract
Epithelioid trophoblastic tumor(ETT)is an exceedingly rare subset of gestational trophoblastic neoplasia(GTN)that typically arises in the lower uterine segment or cervix and is classically associated with a history of amenorrhea and only modestly elevated serum human chorionic gonadotropin(hCG).Because of its non-specific clinical presentation and the frequently low hCG levels,diagnosis is challenging and requires integrated evaluation of clinical history,morphology,and immunohistochemistry.We report a woman with prior amenorrhea who presented with acute life-threatening vaginal bleeding,a cervical mass,and low serum hCG.Owing to overlapping morphologic and immunophenotypic features with cervical carcinoma,the differential diagnosis was complex.After emergent uterine artery embolization,the patient underwent laparoscopic hysterectomy with bilateral salpingo-oophorectomy and achieved an excellent outcome.This case underscores the necessity of including ETT in the differential diagnosis of atypical cervical neoplasms to avoid misdiagnosis and ensure timely,effective therapy.关键词
滋养层肿瘤/子宫出血/子宫动脉栓塞术/生育力保存/上皮样滋养细胞肿瘤Key words
Trophoblastic neoplasms/Uterine hemorrhage/Uterine artery embolization/Fertility preservation/Epithelioid trophoblastic tumor引用本文复制引用
香惠华,吴珮君,何欣怡,叶飞,罗新,林伟钊,舒珊荣..以阴道大出血为首发症状的宫颈上皮样滋养细胞肿瘤成功治疗一例[J].国际妇产科学杂志,2026,53(1):27-32,6.
