摘要
Abstract
Objective To explore the electrocardiographic differential diagnosis between hypertensive left ventricular hypertrophy(H-LVH)and hypertrophic cardiomyopathy(HCM).Methods Ninety patients with H-LVH(H-LVH group)and 60 patients with HCM(HCM group)were selected.All patients underwent surface 12-lead electrocardiogram(ECG)examination.The Tpeak-Tend(Tp-e)interval in limb leads and precordial leads were compared between the two groups.The minimum Tp-e interval,the maximum Tp-e interval,and corrected Tp-e interval were also compared.Electrocardiographic dispersion parameters were recorded,including QT dispersion(QTd),the maximum QT interval,and the minimum QT interval.ROC curve analysis was used to evaluate the area under the curve(AUC)for the differential diagnosis of H-LVH and HCM using Tp-e intervals in each lead.Results Compared with the H-LVH group,the Tp-e intervals in leads Ⅰ,Ⅱ,aVR,aVF,V5,and V6 were all significantly increased in the HCM group(P<0.01).The average minimum Tp-e interval,maximum Tp-e interval,and corrected Tp-e interval were all significantly longer in the HCM group than those in the H-LVH group(P<0.01).The maximum QT interval,minimum QT interval,and QTd in the H-LVH group were all significantly lower than those in the HCM group(all P<0.05).The Tp-e interval yielded the largest AUC value in lead Ⅱ among all leads,reaching 0.83(95%CI 0.71-0.96,P<0.01).Conclusion The manifestations of surface 12-lead ECG are significantly different between patients with H-LVH and HCM.There are certain differences in electrocardiographic dispersion between the two diseases.The minimum Tp-e interval,maximum Tp-e interval,corrected Tp-e interval,and Tp-e interval in lead Ⅱ have high value for the differential diagnosis between H-LVH and HCM.关键词
肥厚型心肌病/高血压性左心室肥厚/体表12导联心电图/T波峰-末间期Key words
hypertrophic cardiomyopathy/hypertensive left ventricular hypertrophy/surface 12-lead electrocardiogram/Tpeak-Tend interval分类
医药卫生