菌物学报2026，Vol.45Issue(3)：1-18,18.DOI:10.13346/j.mycosystema.250269
猴头菇多糖的化学修饰及其生物活性研究进展
Research advance in the chemical modification methods and the biological activities of Hericium erinaceus polysaccharides:a review
摘要
Abstract
Hericium erinaceus polysaccharides as the main active component extracted from H.erinaceus have many biological activities such as anti-oxidation,anti-tumor,and immune regulation.However,there are some limitations in solubility,bioavailability and activity intensity of natural H.erinaceus polysaccharides.In recent years,certain progress has been made in the studies of chemical modification,and structural features,having effects on the biological activities of H.erinaceus polysaccharides.In this paper,the recent advances in the study of chemical modification and biological activities of H.erinaceus polysaccharides are summarized,and the chemical modification methods of H.erinaceus polysaccharides through introducing new functional groups to substitute hydroxyl groups on the polysaccharide chains are elucidated.The changes in the structure and physicochemical properties of the chemically modified H erinaceus polysaccharides are introduced,and the alterations in biological activities and the underlying mechanisms of the chemically modified H.erinaceus polysaccharides are analyzed and discussed.It is expected that this work might provide a theoretical basis for further exploration of modification of H.erinaceus polysaccharides.关键词
猴头菇多糖/化学修饰/结构特征/生物活性/机理Key words
Hericium erinaceus polysaccharides/chemical modification/structural characteristics/biological activities/mechanisms引用本文复制引用
王舰,蔡高袁,吴莲花,李伶俐,孙培龙,杨开..猴头菇多糖的化学修饰及其生物活性研究进展[J].菌物学报,2026,45(3):1-18,18.基金项目
浙江省"尖兵领雁+X"科技计划项目(2025C01101) （2025C01101）
浙江省自然科学基金(LLSSZ25C200001) This work was supported by the Zhejiang Provincial Key Research and Development Program(2025C01101)and the Zhejiang Provincial Natural Science Foundation(LLSSZ25C200001). （LLSSZ25C200001）
