菌物学报2026，Vol.45Issue(3)：78-87,10.DOI:10.13346/j.mycosystema.250178
自噬蛋白CfAtg7在果生刺盘孢中的功能
Functions of autophagy protein CfAtg7 in Colletotrichum fructicola
摘要
Abstract
Anthracnose is prevalent in major oil-tea production regions across the country,severely compromising yield and quality of oil-tea Camellia oleifera.Colletotrichum fructicola is the dominant pathogenic fungus responsible for this disease,and understanding its pathogenic mechanisms is fundamental for controlling Ca.oleifera anthracnose.In eukaryotes,autophagy is a conserved intracellular degradation pathway and serves as the primary route for degrading macromolecular proteins and damaged organelles.Atg7,a core autophagy protein,plays crucial roles in many plant-pathogenic fungi.However,its biological functions in Co.fructicola remains unclear.In this study,the CfATG7 gene knockout mutant ΔCfatg7 and its complementary strain ΔCfatg7/CfATG7 were constructed,and their phenotype and pathogenicity were assayed.The results demonstrate that CfAtg7 is involved in regulating autophagy,vegetative growth,conidiation,and appressorium formation.It also participates in the responses to endoplasmic reticulum stress,cell wall integrity stress,and oxidative stress,revealing the pleiotropic roles of the autophagy protein CfAtg7 in Co.fructicola.This study elucidated the biological functions of CfAtg7 in Co.fructicola,providing experimental evidence for the development of novel fungicides targeting this protein.关键词
油茶/果生刺盘孢/自噬相关蛋白/CfAtg7Key words
Camellia oleifera/Colletotrichum fructicola/autophagy-related protein/CfAtg7引用本文复制引用
陈妍,王伊玲,罗晶,张盛培..自噬蛋白CfAtg7在果生刺盘孢中的功能[J].菌物学报,2026,45(3):78-87,10.基金项目
湖南省自然科学基金(2023JJ20100) （2023JJ20100）
国家自然科学基金(32001317) （32001317）
国家重点研发计划(2023YFD1401301) This work was supported by the Natural Science Foundation of Hunan Province(2023JJ20100),the National Natural Science Foundation of China(32001317),and The National Key Research&Development Program of China(2023YFD1401301). （2023YFD1401301）
