南京医科大学学报（自然科学版）2026，Vol.46Issue(3)：396-402,412,8.DOI:10.7655/NYDXBNSN251161
育龄女性体力活动水平及静坐时间与月经周期异常的关联研究
The association between physical activity and sedentary time with irregular menstrual cycles in reproductive women:a cross-sectional study
摘要
Abstract
Objective:To explore the relationship between physical activity,sedentary time,and irregular menstrual cycles in women of reproductive age.Methods:Conducted between April and June 2024 using convenience sampling,the cross-sectional study assessed physical activity and sedentary time through the international physical activity questionnaire-short form(IPAQ-SF),while menstrual cycles were self-reported.Associations were analyzed using logistic regression and restricted cubic spline models,with E-values calculated to assess the influence of potential unmeasured confounders.Results:A total of 1 259 participants were included,with a mean age of 25.0±5.3 years.The moderate physical activity was linked to a 40%lower risk of irregular menstrual cycles compared to low activity(OR=0.60,95%CI:0.44-0.81),and high physical activity was associated with a 46%reduced risk(OR=0.54,95%CI:0.37-0.79),after adjusting for all covariates.Meeting World Health Organization guidelines for moderate-to-vigorous activity was associated with a 36%decreased risk(OR=0.64,95%CI:0.48-0.85).No statistically significant association was observed between sedentary time and irregular menstrual cycles.E-value analysis suggested that unmeasured confounders would need a moderate association strength(1.8-2.1)with both exposure and outcome to negate these findings.The risk of irregular menstrual cycles began to rise when weekly total metabolic equivalents exceeded 3 185 min.Conclusion:Moderate to high physical activity levels are inversely related to irregular menstrual cycles in reproductive-aged women,though excessively high activity may increase risk.Ensuring adequate physical activity appears more crucial than merely reducing sedentary behavior.关键词
月经周期异常/体力活动/静坐时间/育龄女性Key words
irregular menstrual cycle/physical activity/sedentary time/reproductive women分类
医药卫生引用本文复制引用
李红乔,黄玲玲,王欣茹,张祎,赵梦洁,郑含月,王蓓,张学宁,洪翔..育龄女性体力活动水平及静坐时间与月经周期异常的关联研究[J].南京医科大学学报（自然科学版）,2026,46(3):396-402,412,8.基金项目
国家自然科学基金(82574109) （82574109）
江苏省妇幼保健科研项目(F202303) （F202303）
