南京医科大学学报（自然科学版）2026，Vol.46Issue(3)：403-412,10.DOI:10.7655/NYDXBNSN250971
术前左心室射血分数作为迷宫Ⅳ射频消融联合瓣膜术后房颤复发独立预测因子的倾向性评分匹配研究
Preoperative left ventricular ejection fraction as an independent predictor for atrial fibrillation recurrence after Maze Ⅳ combined with valve surgery:a propensity score-matched study
摘要
Abstract
Objective:To explore the influence of preoperative left ventricular ejection fraction(LVEF)on the risk of atrial fibrillation(AF)recurrence after combined Cox Maze Ⅳ and valvular surgery.Methods:We retrospectively reviewed clinical and follow up data of patients who underwent Cox Maze Ⅳ combined with valvular surgery at the Department of Cardiothoracic and Vascular Surgery,the First Affiliated Hospital of Nanjing Medical University,between January 2014 and December 2023.Patients were classified by echocardiographic LVEF measured within one week before surgery into a low LVEF group(LVEF<50%)and a normal LVEF group(LVEF≥50%).Propensity score matching(PSM)was performed at a 1∶2 ratio to balance baseline covariates between groups.Postoperative AF recurrence rates were compared between matched groups.Results:A total of 513 patients were initially included.Before matching,the low LVEF group comprised 66 patients(39 males,27 females)with a mean age of(59.7±8.7)years,while the normal LVEF group comprised 447 patients(179 males,268 females)with a mean age of(59.4±9.5)years.After PSM,64 patients remained in the low LVEF group and 125 in the normal LVEF group.The postoperative AF recurrence rate was significantly higher in the low LVEF group compared to the normal LVEF group(log-rank,P=0.013).Cox regression analysis identified low LVEF as an independent risk factor for AF recurrence after Cox-Maze Ⅳ combined with valvular surgery.Conclusion:Lower preoperative LVEF is associated with a higher risk of AF recurrence after combined Cox MazeⅣand valvular surgery.关键词
左心室射血分数/心房颤动/迷宫Ⅳ手术/倾向性评分匹配Key words
left ventricular ejection fraction/atrial fibrillation/Cox-Maze Ⅳ procedure/propensity score matching分类
医药卫生引用本文复制引用
葛愿,蔡岩坡,李明辉,顾嘉玺..术前左心室射血分数作为迷宫Ⅳ射频消融联合瓣膜术后房颤复发独立预测因子的倾向性评分匹配研究[J].南京医科大学学报（自然科学版）,2026,46(3):403-412,10.基金项目
国家自然科学基金(82200340) （82200340）
