南京中医药大学学报2026，Vol.42Issue(2)：220-227,8.DOI:10.14148/j.issn.1672-0482.2026.0220
基于白色脂肪棕色化的辛热中药成分减肥作用研究进展
Research Progress on Anti-Obesity Effect of Components from Pungent-Hot Chinese Herbal Medicines Based on White Adipose Tissue Browning
摘要
Abstract
Pungent-hot(including pungent-warm)components from Chinese herbal medicines can effectively treat obesity due to their yang-warming effect,and their main mechanism of action is related to promote white adipose tissue browning.On the basis of summarizing the role of white adipose tissue browning,this article systematically reviews the fat-reducing effect and mechanism of pungent-hot Chinese herbal components in promoting white adipose tissue browning in recent years,and finds that capsaicin and cinna-maldehyde are the main representative components,with a synergistic effect with cold environment.This article also focuses on discuss-ing the application prospects of local delivery of pungent-hot Chinese herbal components for thermogenic fat reduction,and puts for-ward three aspects of prospects:exploring new mechanisms,applying new technologies,and developing sesquiterpene components for local fat reduction.This article will provide a scientific basis for the development of fat-reducing applications of pungent-hot Chinese herbal components,and offer new ideas for the medicinal property characterization of pungent-hot Chinese herbal medicines based on adipocyte thermogenesis.关键词
辛热中药成分/白色脂肪棕色化/减肥作用/药性表征/局部减肥/辣椒素/桂皮醛Key words
pungent-hot components from Chinese herbal medicines/white adipose tissue browning/fat-reducing effect/medicinal property characterization/local fat reduction/capsaicin/cinnamaldehyde分类
医药卫生引用本文复制引用
何天雨,李其彬,李珊,方彭华,叶亮,田荣,陈军..基于白色脂肪棕色化的辛热中药成分减肥作用研究进展[J].南京中医药大学学报,2026,42(2):220-227,8.基金项目
国家自然科学基金面上项目(82173994) （82173994）
江苏省研究生科研创新计划(KYCX25_2371) （KYCX25_2371）
