南京中医药大学学报2026，Vol.42Issue(2)：228-238,11.DOI:10.14148/j.issn.1672-0482.2026.0228
中药活性成分调控胆汁酸抗肥胖作用机制研究进展
Research Progress on the Action Mechanisms of Traditional Chinese Medicine Active Components Regu-lating Bile Acid Metabolism for Anti-Obesity Effects
摘要
Abstract
In recent years,regulating bile acid metabolism to improve metabolic homeostasis has become an emerging research hotspot in the field of obesity prevention and treatment.Traditional Chinese medicine(TCM)active components(such as saponins,polysaccharides,flavonoids,and alkaloids)can influence bile acid metabolism through various pathways.Based on this,this article systematically reviews the recent research progress on the anti-obesity effects of TCM through regulating bile acid metabolism,aim-ing to provide a basis for subsequent clinical validation and offer new TCM strategies for the prevention and treatment of metabolic diseases.关键词
肥胖/胆汁酸代谢/肠道菌群/中药/皂苷/多糖/多酚/黄酮/生物碱Key words
obesity/bile acid metabolism/gut microbiota/TCM/saponins/polysaccharides/polyphenols/flavonoids/alkaloids分类
医药卫生引用本文复制引用
侯熊琳,罗子宸,黄怡,时晨,谢彤,周希乔,单进军..中药活性成分调控胆汁酸抗肥胖作用机制研究进展[J].南京中医药大学学报,2026,42(2):228-238,11.基金项目
国家自然科学基金面上项目(82474206) （82474206）
江苏省基础研究计划(BK20250763) （BK20250763）
中国博士后科学基金面上资助(2025M773906) （2025M773906）
国家资助博士后研究人员计划(GZC20252591) （GZC20252591）
江苏省高等学校基础科学(自然科学)研究项目(25KJB360009) （自然科学）
江苏省中医流派研究院重点课题(LPZD2025012) （LPZD2025012）
南京中医药大学揭榜挂帅重大项目(JBGS202401) （JBGS202401）
