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客观睡眠时间短与慢性失眠障碍患者血脂异常的相关性

周女诗 彭旭梅 曹智玥 刘程程 姚静

四川精神卫生2026,Vol.39Issue(1):58-62,5.
四川精神卫生2026,Vol.39Issue(1):58-62,5.DOI:10.11886/scjsws20250304001

客观睡眠时间短与慢性失眠障碍患者血脂异常的相关性

Correlation between objective short sleep duration and dyslipidemia in patients with chronic insomnia disorder

周女诗 1彭旭梅 1曹智玥 1刘程程 1姚静2

作者信息

  • 1. 川北医学院临床医学院,四川 南充 637000||四川省精神卫生中心·绵阳市第三人民医院,四川 绵阳 621000
  • 2. 四川省精神卫生中心·绵阳市第三人民医院,四川 绵阳 621000
  • 折叠

摘要

Abstract

Background Chronic insomnia disorder has become a significant public health issue,and it may be associated with dyslipidemia.Previous studies on dyslipidemia in patients with chronic insomnia disorder have mainly focused on exploring the relationship between subjective short sleep duration and dyslipidemia,while there have been limited studies on the relationship between objective short sleep duration and dyslipidemia.Objective To explore the relationship between objective short sleep duration and dyslipidemia in patients with chronic insomnia disorder,in order to provide references for the prevention and intervention of dyslipidemia in this population.Methods A total of 103 patients who were hospitalized at The Third Hospital of Mianyang from August 2022 to November 2023 and met the diagnostic criteria for chronic insomnia disorder as defined in the International Classification of Sleep Disorder,third edition(ICSD-3)were retrospectively collected.The objective sleep duration of the patients was obtained through polysomnography.The patients were divided into two groups based on their objective sleep duration:the group with objective sleep duration≥7 hours(n=71)and the group with objective sleep duration<7 hours(n=32).Binary Logistic regression analysis was used to explore the impact of objective sleep duration<7 hours on dyslipidemia.Results Among 103 patients with chronic insomnia disorder,59 cases(57.28%)were identified with dyslipidemia.The comparison of dyslipidemia conditions between the group with objective sleep duration≥7 hours and the group with objective sleep duration<7 hours showed a statistically significant difference(χ2=5.956,P<0.05).Compared with the group with objective sleep duration≥7 hours,the group with objective sleep duration<7 hours exhibited significantly lower high-density lipoprotein cholesterol levels,and reduced sleep efficiency(t=-2.003,-5.482,P<0.05 or 0.01).Binary Logistic regression analysis results showed that the risk of abnormal blood lipids in patients with chronic insomnia disorder with objective sleep duration<7 hours was 3.128 times higher than that of patients with objective sleep duration≥7 hours(OR=3.128,95%CI:1.139-8.588).Conclusion Objective short sleep duration may be a risk factor for dyslipidemia in patients with chronic insomnia disorder.

关键词

慢性失眠障碍/客观睡眠时间/血脂异常/血脂谱

Key words

Chronic insomnia disorder/Objective sleep duration/Dyslipidemia/Lipid profile

分类

医药卫生

引用本文复制引用

周女诗,彭旭梅,曹智玥,刘程程,姚静..客观睡眠时间短与慢性失眠障碍患者血脂异常的相关性[J].四川精神卫生,2026,39(1):58-62,5.

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