陕西医学杂志2026，Vol.55Issue(3)：334-338,5.DOI:10.3969/j.issn.1000-7377.2026.03.007
超声权重评分联合血清Tg-Ab、TPO-Ab水平在甲状腺结节良恶性鉴别中的价值研究
Value of ultrasound weight score combined with serum Tg-Ab and TPO-Ab levels in differentiation of benign and malignant thyroid nodules
摘要
Abstract
Objective:To investigate the value of ultrasound weight score combined with serum anti-thyroglobu-lin antibody(Tg-Ab)and anti-thyroid peroxidase antibody(TPO-Ab)levels in the differentiation of benign and ma-lignant thyroid nodules.Methods:A total of 93 patients with thyroid nodules were selected and divided into two groups according to pathological results,namely benign group(n=64)and malignant group(n=29).The ultrasound weight score,and serum TG-Ab,TPO-Ab,Tg,TSH levels were compared between the two groups.The value of ul-trasound weight score combined with serum Tg-Ab,TPO-Ab levels in differentiating benign and malignant thyroid nodules was analyzed.Results:There were 101 thyroid nodules in 93 patients.Benign thyroid nodules accounted for 65.35%(66/101),and malignant accounted for 34.65%(35/101).Compared with the benign group,the ultrasound weight score,serum TG-Ab,TPO-Ab,Tg and TSH levels in the malignant group were significantly higher(all P<0.05).The AUC value of ultrasound weight score combined with serum Tg-Ab and TPO-Ab levels in the differential diagnosis of benign and malignant thyroid nodules was 0.904,which was significantly higher than that of the three independent tests(all P<0.05).Conclusion:Tg-Ab and TPO-Ab may be involved in the occurrence and development of malignant thyroid nodules.Moreover,the combined use of ultrasound weight score and serum Tg-Ab and TPO-Ab levels has good differential value for benign and malignant thyroid nodules.关键词
甲状腺结节/恶性/超声权重评分/抗甲状腺球蛋白抗体/抗甲状腺过氧化物酶抗体/鉴别价值Key words
Thyroid nodules/Malignant/Ultrasound weight score/TG-Ab/TPO-Ab/Differential value分类
医药卫生引用本文复制引用
李秋雨,陈静静,王鑫,郑骄阳,芦润清,张家齐..超声权重评分联合血清Tg-Ab、TPO-Ab水平在甲状腺结节良恶性鉴别中的价值研究[J].陕西医学杂志,2026,55(3):334-338,5.基金项目
国家自然科学基金资助项目(81800865) （81800865）
上海市自然科学基金资助项目(JCZRYB202401301) （JCZRYB202401301）
