时珍国医国药2026，Vol.37Issue(4)：673-684,12.DOI:10.70976/j.1008-0805.SZGYGY-2026-0410
孟河医派特色炮制辅料猪心血和猪血冻干粉质量标准研究
Quality standard research on freeze-dried powders of porcine cardiac blood and porcine blood as characteristic processing excipients of Menghe medical school
摘要
Abstract
Objective To establish the quality standard for porcine cardiac blood(PCB)and porcine blood(PB)as processing excipi-ents of Menghe Medical School.Methods Fifteen batches of PCB and PB samples(as freeze-dried powders)were collected.They were identified by traits,polymerase chain reaction(PCR),infrared spectroscopy,and peptide fingerprinting combined with chemometrics.The contents of moisture,total ash,acid-insoluble ash,extract,iron,nitrogen,transferrin(Tf),and hydrolyzed amino acids were determined.Results The samples were systematically analyzed using the established methods.The results showed that PCB,PB,and other animal blood could be differentiated by PCR.PCB and PB could be distinguished by infrared spectroscopy and peptide fingerprint-ing combined with chemometrics.It was recommended that the moisture content in both PCB and PB should not exceed 8.0%;the total ash in PCB should not exceed 8.0%,and that in PB should not exceed 11.0%;the acid-insoluble ash in PCB should not exceed 0.50%,and that in PB should not exceed 1.20%;the extract content should not be less than 42.0%;the nitrogen content should not be less than 10.0%;the Tf content should not be less than 0.10%;the iron content in PCB should not be less than 0.20%,and that in PB should not be less than 0.18%;the hydrolyzed amino acids content in PCB should not be less than 36.0%,and that in PB should not be less than 32.0%.Conclusion This study supplements and improves the quality evaluation criteria for PCB and PB as excipients,provid-ing a scientific basis for establishing quality standards for PCB,PB,and their processed decoction pieces.关键词
孟河医派/猪心血/猪血/指纹图谱/聚合酶链式反应/质量标准Key words
Menghe medical school/Porcine cardiac blood/Porcine blood/Fingerprint/Polymerase chain reaction/Qual-ity standard分类
医药卫生引用本文复制引用
李婷,颜晓静,刘楠,王地均,廉源沛,尹春燕,蔡佳丽,周世康,刘产明,黄玮..孟河医派特色炮制辅料猪心血和猪血冻干粉质量标准研究[J].时珍国医国药,2026,37(4):673-684,12.基金项目
国家自然科学基金(82074016 （）
81603296) （）
江苏省中医药管理局项目(2020ZX18) （2020ZX18）
常州市卫生健康委员会重大项目(ZD202028) （ZD202028）
常州市科技计划项目(CM20223006) （CM20223006）
江苏省研究生科研创新计划项目(SJCX24_0918) （SJCX24_0918）
