时珍国医国药2026，Vol.37Issue(4)：732-737,6.DOI:10.70976/j.1008-0805.SZGYGY-2026-0419
中医药改善多囊卵巢综合征子宫内膜容受性的研究进展
Research progress on the enhancement of endometrial receptivity in polycystic ovary syn-drome by traditional Chinese medicine
摘要
Abstract
Polycystic ovary syndrome(PCOS)is a major cause of infertility in women of reproductive age,with current treatments pri-marily focusing on ovulation induction and assisted reproductive technology(ART).However,endometrial receptivity dysfunction in PCOS patients,caused by factors such as sex hormone imbalance,glucose and lipid metabolism disorders,and local endometrial inflam-mation,remains a key obstacle to successful pregnancy.Recent studies have shown that traditional Chinese medicine(TCM)can enhance endometrial receptivity in PCOS through multiple pathways:enhancing endometrial blood supply,regulating the decidualiza-tion process and gut microbiota composition to optimize endometrial morphology and function;modulating signaling pathways including PI3K/AKT,TLR4/NF-κB/NLRP3,Wnt/β-catenin,and MAPK/ERK to promote endometrial angiogenesis and enhance the immune microenvironment;while also mitigating potential endometrial damage from hormonal and ovulation-inducing drugs during ART.This article systematically reviews the applications and mechanisms of TCM in enhancing endometrial receptivity in PCOS,aiming to provide new insights for enhancing fertility in PCOS patients.关键词
多囊卵巢综合征/子宫内膜容受性/中医药/作用机制/信号通路Key words
Polycystic ovary syndrome/Endometrial receptivity/Traditional Chinese medicine/Functional mechanism/Sig-naling pathway分类
医药卫生引用本文复制引用
冷亚文,王宇,吴效科..中医药改善多囊卵巢综合征子宫内膜容受性的研究进展[J].时珍国医国药,2026,37(4):732-737,6.基金项目
黑龙江省卵巢疾病研究中心项目(LC2020R009) （LC2020R009）
中医药循证能力提升项目(国中医药科技中药便函[2023]24号) （国中医药科技中药便函[2023]24号）
