日用化学品科学2026，Vol.49Issue(3)：53-61,9.DOI:10.3969/j.issn.1006-7264.2026.03.008
浙江红山茶籽油脂质组成及舒缓修护功效研究
Study on the lipid composition and soothing and repairing efficacy of Camellia Chekiangoleosa seed oil
邓全知 1曹义苗 1高聪 1尹世鹏 1赵前前 1高宏旗1
作者信息
- 1. 上海林清轩化妆品集团股份有限公司 科研中心,上海 201612
- 折叠
摘要
Abstract
To systematically characterize the lipid composition of Zhejiang Camellia Chekiangoleosa seed oil and evaluate its soothing and repairing effects on damaged cells,UPLC-QTRAP-MS/MS technology was used to qualitatively and quantitatively analyze its lipid composition through ESI positive and negative ion scanning mode.The LPS induced RAW264.7 macrophage inflammation model and HaCaT cell scratch model were used to evaluate its inhibitory ability on TNF-α and IL-6 and its promoting effect on cell migration,respectively.The results showed that CCSO contains 369 types of lipid components in 6 major categories,which include glycerides accounting for 98.54％(311 types),glycerophospholipids accounting for 1.16％(26 types),sphingolipids(16 types,approximately 186 μg/g),free fatty acids 0.13％(11 types),sterol esters 0.16％(2 types),and isoprenol esters(2 types,70 μg/g);CCSO can significantly inhibit the release of inflammatory factors TNF-α and IL-6,and effectively promote the epidermal cell repair.关键词
浙江红山茶籽油/脂质组学/舒缓/屏障修复/UPLC-QTRAP-MS/MSKey words
Zhejiang Camellia Chekiangoleosa seed oil/lipidomics/soothing/barrier repair/UPLC-QTRAP-MS/MS分类
化学化工引用本文复制引用
邓全知,曹义苗,高聪,尹世鹏,赵前前,高宏旗..浙江红山茶籽油脂质组成及舒缓修护功效研究[J].日用化学品科学,2026,49(3):53-61,9.
