现代中西医结合杂志2026，Vol.35Issue(2)：147-153,7.DOI:10.3969/j.issn.1008-8849.2026.02.001
基于子午流注理论探究正常高值血压人群血压节律与时辰血压的特点
Characteristics of blood rhythm and two-hour period blood pressure in high-normal blood pressure population based on midnight-noon ebb-flow theory
摘要
Abstract
Objective It is to explore the characteristics of blood pressure rhythm and two-hour period blood pressure in the people with high-normal blood pressure based on midnight-noon ebb-flow theory.Methods A total of 247 individuals with high-normal blood pressure in the surrounding communities of Dongzhimen Hospital of Beijing University of Chinese Medicine and Guang'anmen Hospital of Chinese Academy of Traditional Chinese Medicine from September 2019 to Septem-ber 2022 were collected as the subjects.Their basic information was collected and 24-hour ambulatory blood pressure moni-toring was completed or supplied,the timing of peak systolic blood pressure(SBP)over 24 hours was analyzed with circu-lar distribution analysis,and dynamic blood pressure indicators and two-hour period SBP were compared among individuals with different blood pressure rhythms.Results Twenty-four cases with incomplete data or missing ambulatory blood pressure measurements were eliminated,and a total of 223 cases were included in the analysis.The peak SBP concentrated from Chen time to Xu time(8:58:02-19:15:31).Blood pressure rhythms were classified as dipper type in 43 cases(dipper group),non-dipper type in 159 cases(non-dipper group),and reverse dipper type in 21 cases(reverse dipper group).The age of subjects in both the non-dipper and reverse dipper groups was significantly higher than that in the dipper group(both P<0.05).Night mean systolic blood pressure(nSBP)and night mean diastolic blood pressure(nDBP)from high to low were as follows:reverse-dipper group>non-dipper group>dipper group,the differences were all statistically signifi-cant(all P<0.05);the24-hour mean heart rate(24hHR)and daytime mean heart rate(dHR)of subjects in the re-verse-dipper group were significantly slower than those of subjects in the dipper group(all P<0.05).There were signifi-cant differences in two-hour period SBP from Hai time to Chen time and in two-hour period DBP from Zi time to Mao time among the three groups(all P<0.05),and the SBP and DBP were higher in the reverse-dipper group and non-dipper group.Conclusion The peak value of 24-hour SBP in the high-normal blood pressure population is concentrated from Chen time to Xu time,and the blood pressure rhythm is mainly non-dipper pattern,already with abnormal blood pressure rhythm.The individuals with abnormal rhythms may have higher blood pressure from Hai time to Chen time,blood pressure fluctuations may be related to the two-hour periods.关键词
正常高值血压/子午流注/动态血压/血压节律/时间医学/十二时辰Key words
high-normal blood pressure/midnight-noon ebb-flow theory/ambulatory blood pressure/blood pressure rhythm/chronomedicine/twelve two-hour periods分类
医药卫生引用本文复制引用
王尔玉,邢雁伟,常佩芬,苏红,魏大为,李昕晔,杨燕,贺小芳,张楠楠,孔令旗,王秋月..基于子午流注理论探究正常高值血压人群血压节律与时辰血压的特点[J].现代中西医结合杂志,2026,35(2):147-153,7.基金项目
国家重点研发计划项目(2018YFC1704901) （2018YFC1704901）
