首页|期刊导航|中国病毒学|Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins

Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins

Yingying Yu Cao-Qi Lei Shuai Xu Qiyun Zhu Qian Wang Yanli Wei Junwen Liu Guangwen Wang Zhengxiang Wang Wentao Shen Lu Han Chengjun Li

中国病毒学2025，Vol.40Issue(3)：388-400,13.

中国病毒学2025，Vol.40Issue(3)：388-400,13.DOI:10.1016/j.virs.2025.04.007

Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins

Yingying Yu ¹Cao-Qi Lei ²Shuai Xu ³Qiyun Zhu ¹Qian Wang ¹Yanli Wei ¹Junwen Liu ¹Guangwen Wang ⁴Zhengxiang Wang ¹Wentao Shen ¹Lu Han ¹Chengjun Li⁴

作者信息

1. State Key Laboratory for Animal Disease Control and Prevention,College of Veterinary Medicine,Lanzhou University,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,730000,China
2. State Key Laboratory of Virology,College of Life Sciences,Wuhan University,Wuhan,430072,China
3. State Key Laboratory for Animal Disease Control and Prevention,College of Veterinary Medicine,Lanzhou University,Lanzhou Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Lanzhou,730000,China||Gansu Province Research Center for Basic Disciplines of Pathogen Biology,Lanzhou,730046,China
4. State Key Laboratory for Animal Disease Control and Prevention,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin,150069,China
折叠

摘要

关键词

Nucleophosmin-1(NPM1)/Influenza A virus(IAV)/RNA binding/Viral RNA/Viral polymerase

Key words

Nucleophosmin-1(NPM1)/Influenza A virus(IAV)/RNA binding/Viral RNA/Viral polymerase

引用本文复制引用

Yingying Yu,Cao-Qi Lei,Shuai Xu,Qiyun Zhu,Qian Wang,Yanli Wei,Junwen Liu,Guangwen Wang,Zhengxiang Wang,Wentao Shen,Lu Han,Chengjun Li..Nucleophosmin 1 inhibits the replication of influenza A virus by competitively binding viral RNA with viral proteins[J].中国病毒学,2025,40(3):388-400,13.

基金项目

We thank Susan Watson for editing the manuscript.We appreciate the gift of the H3N2 virus from Prof.Yihong Xiao at the Shandong Agricul-tural University(China).This study was supported by funding from the National Natural Science Foundation of China(U23A20243 and 32272972 to QZ,32172820 to SX),the Major Science and Technology Project of Gansu Province(22ZD6NA001 to SX),the Youth Innovation Program(Y2023QC30)and the Agricultural Science and Technology Innovation Program(CAAS-ASTIP-JBGS-20210102 to SX)of the Chinese Academy of Agricultural Sciences. （China）

中国病毒学

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ISSN：1003-5125

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