Human endogenous retrovirus W family envelope protein(ERVWE1)regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia
Jiahang Zhang Xu Zhang Chen Jia Fan Zhu Huiling Wang Xing Xue Xiulin Wu Wenshi Li Zhao Lv Yaru Su Mengqi Zhang Kexin Zhao
中国病毒学2025，Vol.40Issue(3)：401-418,18.
中国病毒学2025，Vol.40Issue(3)：401-418,18.DOI:10.1016/j.virs.2025.05.007
Human endogenous retrovirus W family envelope protein(ERVWE1)regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia
Human endogenous retrovirus W family envelope protein(ERVWE1)regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia
摘要
关键词
Human endogenous retroviruses(HERVs)/ERVWE1/NADPH oxidase activator 1(NOXA1)/Macroautophagy/Micromitophagy/SchizophreniaKey words
Human endogenous retroviruses(HERVs)/ERVWE1/NADPH oxidase activator 1(NOXA1)/Macroautophagy/Micromitophagy/Schizophrenia引用本文复制引用
Jiahang Zhang,Xu Zhang,Chen Jia,Fan Zhu,Huiling Wang,Xing Xue,Xiulin Wu,Wenshi Li,Zhao Lv,Yaru Su,Mengqi Zhang,Kexin Zhao..Human endogenous retrovirus W family envelope protein(ERVWE1)regulates macroautophagy activation and micromitophagy inhibition via NOXA1 in schizophrenia[J].中国病毒学,2025,40(3):401-418,18.基金项目
This work is supported by the National Natural Science Foundation of China(No.82272321)and the Stanley Foundation from the Stanley Medical Research Institute(SMRI),United States(No.06R-1366).We acknowledge the Medicine Research Center for Structural Biology of Wuhan University for providing the confocal microscopy(Leica-LCS-SP8-STED).We thank the contributors for providing the human schizophrenia datasets with registration numbers GSE53987 and GSE202537(htt p://www.ncbi.nlm.nih.gov/geo).We thank the Renmin Hospital,Wuhan University for providing blood samples from schizophrenia and healthy people. （No.82272321）
