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The coronavirus 3CL protease:Unveiling its complex host interactions and central role in viral pathogenesis

Yecheng Zhang Xinlei Ji Dan Huang Gen Lu Xinwen Chen

中国病毒学2025，Vol.40Issue(4)：509-519,11.

中国病毒学2025，Vol.40Issue(4)：509-519,11.DOI:10.1016/j.virs.2025.07.002

The coronavirus 3CL protease:Unveiling its complex host interactions and central role in viral pathogenesis

Yecheng Zhang ¹Xinlei Ji ²Dan Huang ²Gen Lu ¹Xinwen Chen²

作者信息

1. Department of Respiratory,Guangzhou Women and Children's Medical Center,Guangzhou Medical University,Guangzhou,510623,China
2. Guangzhou National Laboratory,Guangzhou,510005,China
折叠

摘要

关键词

Coronavirus/3CL protease/Virus-host interactions/Innate immunity/Viral replication/Pathogenesis

Key words

Coronavirus/3CL protease/Virus-host interactions/Innate immunity/Viral replication/Pathogenesis

引用本文复制引用

Yecheng Zhang,Xinlei Ji,Dan Huang,Gen Lu,Xinwen Chen..The coronavirus 3CL protease:Unveiling its complex host interactions and central role in viral pathogenesis[J].中国病毒学,2025,40(4):509-519,11.

基金项目

We thank Professor Rongjuan Pei(Chinese Academy of Sciences)and the other members of the Chen Xinwen's lab and Lu Gen's lab for their constructive comments.Our work in this area is supported by the Na-tional Natural Science Foundation of China(grant no.82370015). （Chinese Academy of Sciences）

中国病毒学

OACSCD

ISSN：1003-5125

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