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SARS-CoV-2-encoded miR-nsp3-3p promotes pulmonary fibrosis by inhibiting expression of ALCAM

Yang Yang Qiuyue Wu Xueyan Liu Hongjian Zhou Jianzhen Lei Lan Luo Xinyi Xia

中国病毒学2025，Vol.40Issue(4)：560-570,11.

中国病毒学2025，Vol.40Issue(4)：560-570,11.DOI:10.1016/j.virs.2025.06.007

SARS-CoV-2-encoded miR-nsp3-3p promotes pulmonary fibrosis by inhibiting expression of ALCAM

Yang Yang ¹Qiuyue Wu ¹Xueyan Liu ¹Hongjian Zhou ¹Jianzhen Lei ¹Lan Luo ¹Xinyi Xia²

作者信息

1. Institute of Laboratory Medicine,Jinling Hospital,Affiliated Hospital of Medical School,School of Life Sciences,Nanjing University,Nanjing,210002,China
2. Institute of Laboratory Medicine,Jinling Hospital,Affiliated Hospital of Medical School,School of Life Sciences,Nanjing University,Nanjing,210002,China||State Key Laboratory of Analytical Chemistry for Life Science,Nanjing University,Nanjing,210023,China||Jinling Hospital,The First School of Clinical Medicine,Southern Medical University,Nanjing,210002,China
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摘要

关键词

microRNA(miRNA)/SARS-CoV-2/Pulmonary fibrosis/Activated leukocyte cell adhesion molecule(ALCAM)/Epithelial-mesenchymal transition(EMT)

Key words

microRNA(miRNA)/SARS-CoV-2/Pulmonary fibrosis/Activated leukocyte cell adhesion molecule(ALCAM)/Epithelial-mesenchymal transition(EMT)

引用本文复制引用

Yang Yang,Qiuyue Wu,Xueyan Liu,Hongjian Zhou,Jianzhen Lei,Lan Luo,Xinyi Xia..SARS-CoV-2-encoded miR-nsp3-3p promotes pulmonary fibrosis by inhibiting expression of ALCAM[J].中国病毒学,2025,40(4):560-570,11.

基金项目

We thank the Nanjing Jinling Hospital for providing the clinical specimens used for miRNA detection.We are grateful to Prof.Xi Chen and Prof.Wenjie Guo for consultation and instrument availability that supported this work.This study was supported by the National Natural Science Foundations of China(82372342)and the Clinical Diagnosis and Treatment New Technology Project of Jinling Hospital(No.22LCZLXJS40). （82372342）

中国病毒学

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ISSN：1003-5125

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