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基于数据挖掘分析古籍文献治疗骨关节炎用药规律

陈扬 马玮玮 袁启鹏 蔡泽斌 罗序澳 李华南

新中医2026,Vol.58Issue(5):14-21,8.
新中医2026,Vol.58Issue(5):14-21,8.DOI:10.13457/j.cnki.jncm.2026.05.003

基于数据挖掘分析古籍文献治疗骨关节炎用药规律

Analysis of Medication Rules for Treating Osteoarthritis in Ancient Traditional Chinese Medicine Books Based on Data Mining

陈扬 1马玮玮 1袁启鹏 1蔡泽斌 1罗序澳 1李华南2

作者信息

  • 1. 江西中医药大学临床医学院,江西 南昌 330004
  • 2. 江西中医药大学临床医学院,江西 南昌 330004||江西中医药大学附属医院,江西 南昌 330006
  • 折叠

摘要

Abstract

Objective:To analyze the medication rules of traditional Chinese medicine(TCM)in the treatment of osteoarthritis(OA)in ancient TCM books using data mining techniques.Methods:Ancient TCM books,including the 5th edition of Zhong Hua Yi Dian(Chinese Medical Classics),were searched and analyzed.Passages related to OA treatment were included.Excel software was used to extract information from relevant formulas.Analysis of the frequency,association,clustering,and complex network of the Chinese medicines was performed.Results:A total of 850 prescriptions involving 620 distinct Chinese medicines were extracted from the ancient TCM books.The three most frequently used Chinese medicines were Angelicae Sinensis Radix,Saposhnikoviae Radix,and Cinnamomi Cortex.The primary therapeutic actions of the Chinese medicines used were deficiency-tonifying,exterior-releasing,blood-invigorating and stasis-dispelling,and interior-warming.The properties and flavors of the herbs were predominantly pungent and warm,with their channel tropism mainly focusing on the spleen,liver,and kidney channels.Through association analysis,cluster analysis,and complex network analysis,Angelicae Sinensis Radix,Saposhnikoviae Radix,and Cinnamomi Cortex were identified as the core medicinal combination for treating OA.Conclusion:The TCM approach to treating OA is often based on the core pathogenesis of"deficiency,""cold,"and"stasis."The selection of Chinese medicines such as Angelicae Sinensis Radix,Saposhnikoviae Radix,Cinnamomi Cortex,Aconiti Lateralis Radix Praeparata,and Angelicae Pubescentis Radix embodies the therapeutic principle of supporting healthy qi to eliminate pathogens,emphasizing a holistic treatment approach.

关键词

骨关节炎/数据挖掘/中医古籍/用药规律

Key words

Osteoarthritis/Data mining/Ancient traditional Chinese medicine books/Medication rules

分类

医药卫生

引用本文复制引用

陈扬,马玮玮,袁启鹏,蔡泽斌,罗序澳,李华南..基于数据挖掘分析古籍文献治疗骨关节炎用药规律[J].新中医,2026,58(5):14-21,8.

基金项目

第二届江西省国医名师邓运明国医名师传承工作室建设项目(赣人社字[2021]201号) (赣人社字[2021]201号)

江西省中医药管理局重点研究室、临床研究基地(第三批)建设项目(赣中医药科教字[2022]8号) (第三批)

江西省科学技术厅省级科技专项基金(科技计划第三批)项目(赣科资发[2024]20号) (科技计划第三批)

新中医

0256-7415

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