中国内镜杂志2026，Vol.32Issue(2)：1-8,8.DOI:10.12235/E20250262
医用生物蛋白胶应用于耳内镜下鼓膜修补术的临床疗效
Clinical efficacy of medical protein glue applied in otoscopic myringoplasty
彭雅欣 1唐婷婷 1何佳娣 1王浩 2李巍2
作者信息
- 1. 徐州医科大学第一临床医学院,江苏 徐州 221004
- 2. 徐州医科大学附属医院耳鼻咽喉头颈外科,江苏 徐州 221002
- 折叠
摘要
Abstract
Objective To analyze the clinical efficacy of medical protein glue applied in otoscopic myringoplasty.Methods A retrospective analysis was conducted on the clinical data of 60 patients with simple tympanic membrane perforation from October 2022 to October 2023 and divided into the study group and the control group according to different surgical methods,with 30 cases in each group.The study group used medical protein glue to bond the residual tympanic membrane and repair materials during the operation.In the control group,gelatin sponge was used to cover and repair the tympanic membrane during the operation.Observe the postoperative tympanic membrane healing conditions(tympanic membrane healing rate,healing time,dry ear time and upper and lower diameters of the external auditory canal)and the occurrence of complications in the two groups of patients;Before and after the operation,pure tone audiometry(500,1 000,2 000,4 000 Hz)was used to measure the air conduction thresholds of the two groups of patients and observe the improvement in hearing.The visual analogue scale(VAS)score was used for scoring to evaluate the degree of postoperative pain in patients.Results There were no statistically significant differences in the postoperative tympanic membrane healing rate,healing time,upper and lower diameters of the external auditory canal,and the incidence of complications between the two groups of patients(P>0.05).The average postoperative air conduction threshold in the study group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).The postoperative ear drying time of the study group was shorter than that of the control group,and the VAS score for pain on the first day after surgery was significantly lower than that of the control group.The differences were statistically significant(P<0.05).Conclusion The application of medical protein glue in otoscopic myringoplasty can effectively decrease the air conduction hearing threshold,shorten the dry ear time,relieve the patient's pain,and does not increase the incidence of complications.It is worthy of clinical promotion and application.关键词
耳内镜/医用生物蛋白胶/明胶海绵/鼓膜穿孔/鼓膜修补术Key words
otoscope/medical protein glue/gelatin foam/tympanic membrane perforation/myringoplasty分类
医药卫生引用本文复制引用
彭雅欣,唐婷婷,何佳娣,王浩,李巍..医用生物蛋白胶应用于耳内镜下鼓膜修补术的临床疗效[J].中国内镜杂志,2026,32(2):1-8,8.
