Abstract
Objective To analyze the effects of nasal high-flow humidification oxygen therapy(HFNC)and high-frequency ventilation on blood gas indicators in painless bronchoscopy.Methods 130 patients who underwent painless bronchoscopy from February 2024 to October 2024 were selected and divided into 3 groups according to the random number table method.Among them,group A(43 cases)was treated with HFNC,group B(43 cases)received high-frequency ventilation treatment,and the control group(44 cases)received continuous positive nasal pressure ventilation treatment.Compare three groups of patients before bronchoscopy(T0),bronchoscope into the tracheal bifurcation(T1),at the end of the examination(T2),30 minutes after the examination(T3),and 2 hours after the examination(T4)the vital signs and blood gas index;Compare the incidence of adverse reactions and the satisfaction of microscopic examination among the three groups of patients.Results The time,interaction and inter group effect of heart rate(HR),respiratory rate(RR),mean arterial pressure(MAP),and arterial partial pressure of carbon dioxide(PaCO2)in the three groups were statistically significant(P<0.05).The time and interaction of and arterial partial pressure of oxygen(PaO2)in the three groups were statistically significant(P<0.05),there was no significant difference in inter group effect(P>0.05).Compared with T0,HR,RR,MAP,PaO2 and PaCO2 of group A and group B at T1,T2 and T3 were significantly higher(P<0.05),and there was no significant change in pH value(P>0.05);At time points T1 and T2,the levels of HR,RR,MAP,PaO2,and PaCO2 in group B were significantly higher than those in group A and the control group,and the differences were statistically significant(P<0.05);At time point T3,the levels of HR,RR,MAP,PaO2 and PaCO2 in group A were significantly higher than those in group B and the control group,and the RR,PaO2 and PaCO2 of group B were significantly higher than those of the control group,with the differences were statistically significant(P<0.05);At the T4 time point,HR,RR,MAP,PaO2,PaCO2 and pH value of the three groups all recovered to the T0 time point.Incidence of adverse reaction of group A 2.33%was lower than that in group B,which was 16.28%and 22.73%in the control group,group A microscopic examination satisfaction was 95.35%,which was significantly higher than group B 81.40%and the control group 65.91%,the differences were statistically significant(P<0.05).Conclusion Compared with traditional nasal continuous positive pressure ventilation treatment,both HFNC and high-frequency ventilation have an improving effect on blood gas indicators in painless bronchoscopy.Moreover,HFNC has a better improvement effect than high-frequency ventilation,a lower total incidence of adverse reactions,and a higher satisfaction rate in bronchoscopy.关键词
无痛支气管镜检查术/经鼻高流量湿化氧疗(HFNC)/高频通气/血气指标/血流动力学指标Key words
painless bronchoscopy/nasal high flow humidification oxygen therapy(HFNC)/high frequency ventilation/blood gas index/hemodynamic index分类
医药卫生
