中国循证儿科杂志2026，Vol.21Issue(1)：57-61,5.DOI:10.3969/j.issn.1673-5501.2026.01.008
重庆市7～14岁健康学龄儿童生物声学脂肪分数参考值的横断面调查
A cross-sectional survey on the establishment of reference values of ultrasound-derived fat fraction in healthy children aged 7 to 14 years in Chongqing,China
摘要
Abstract
Background Ultrasound-derived fat fraction(UDFF)is an emerging ultrasound quantitative analysis technology,but currently there is a lack of reference value range for healthy children.Objective To establish reference values of UDFF in healthy children aged 7 to 14 years in Chongqing,providing diagnostic reference data for the prevention and management of pediatric nonalcoholic fatty liver disease(NAFLD).Design Cross-sectional survey.Methods Data were collected between March 2023 and February 2024 from healthy school-aged children undergoing physical examinations at a primary and secondary school in Chongqing.The dataset included medical history,physical examination parameters,abdominal ultrasound findings,and UDFF values.Reference ranges for UDFF were established using the percentile method.Correlation analyses were performed to examine relationships between UDFF and gender,age,anthropometric measurements,as well as measurement depth.Main Outcome Measures UDFF values range for healthy children aged 7 to 14 years.Results A total of 810 healthy children aged 7 to 14 years were included in the study,with the average age was 11.24±1.89 years.The median UDFF was 3.2%,with a range of 2.0%to 5.8%,and a 95%reference interval of 2.0%～5.2%(P2.5 to P97.5).No statistically significant gender difference was observed(P=0.06).UDFF showed a moderate positive correlation with measurement depth(r=0.59,P<0.001),weak positive correlations with waist circumference and waist-to-height ratio(r≥0.3,P<0.001),and no meaningful correlations with age,height,weight,BMI,hip circumference,and abdominal skinfold thickness(r<0.3,P<0.05).Additionally,UDFF demonstrated a high degree of consistency.Conclusion The study establishes percentile curves of UDFF in healthy children aged 7 to 14 years in Chongqing,offering an important reference for the prevention and diagnosis of hepatic steatosis in children and adolescents.关键词
健康儿童/生物声学脂肪分数/参考值/肝脏脂肪变性Key words
Healthy children/Ultrasound-derived fat fraction/Reference value/Hepatic steatosis引用本文复制引用
胡彩辉,陈镜宇,梁小华,安曦洲,许凤麟,李日娜,余明珠,高洋,钟海英,陈栏灵,陈丽静..重庆市7～14岁健康学龄儿童生物声学脂肪分数参考值的横断面调查[J].中国循证儿科杂志,2026,21(1):57-61,5.基金项目
国家自然科学基金面上项目:82373590 （）
重庆市科学技术局自然科学基金面上项目:CSTB2024NSCQ-MSX0180 （）
重庆市科学技术局重庆市技术创新与应用发展专项重点项目:CSTC2021jscx-gksb-N0001 （）
重庆市科卫联合重点项目:2025ZDXM008 （）
重庆市医学科研项目(卫生健康委员会和科技局联合):2025MSXM138 （卫生健康委员会和科技局联合）
