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Characterizing a murine breast cancer mouse model reveals chromosomal abnormalities in structure and number of single-cell clones and the presence of rare cancer stem cell-like phenotypes

Quy Van-Chanh Le Zsolt Jurányi Hien Le Ivan Kempson Zsuzsa S.Kocsis Sisi Liang Yanrui Li Briony L.Gliddon Sheree Bailey Anh Thai-Quynh Nguyen Tyron Turnbull Stuart M.Pitson

动物模型与实验医学(英文)2026,Vol.9Issue(2):367-377,11.
动物模型与实验医学(英文)2026,Vol.9Issue(2):367-377,11.DOI:10.1002/ame2.70156

Characterizing a murine breast cancer mouse model reveals chromosomal abnormalities in structure and number of single-cell clones and the presence of rare cancer stem cell-like phenotypes

Characterizing a murine breast cancer mouse model reveals chromosomal abnormalities in structure and number of single-cell clones and the presence of rare cancer stem cell-like phenotypes

Quy Van-Chanh Le 1Zsolt Jurányi 2Hien Le 3Ivan Kempson 4Zsuzsa S.Kocsis 2Sisi Liang 1Yanrui Li 5Briony L.Gliddon 6Sheree Bailey 7Anh Thai-Quynh Nguyen 5Tyron Turnbull 8Stuart M.Pitson6

作者信息

  • 1. Future Industries Institute,Adelaide University,Mawson Lakes,South Australia,Australia||School of Pharmacy and Biomedical Science,College of Health,Adelaide University,Adelaide,South Australia,Australia
  • 2. Department of Radiobiology and Diagnostic Onco-Cytogenetics,Centre of Radiotherapy,National Institute of Oncology,Budapest,Hungary
  • 3. Department of Radiation Oncology,Royal Adelaide Hospital,Adelaide,South Australia,Australia
  • 4. Future Industries Institute,Adelaide University,Mawson Lakes,South Australia,Australia||Centre for Pharmaceutical Innovation,School of Pharmacy and Biomedical Science,College of Health,Adelaide University,Adelaide,South Australia,Australia
  • 5. Future Industries Institute,Adelaide University,Mawson Lakes,South Australia,Australia
  • 6. Centre for Cancer Biology,Adelaide University and SA Pathology,Adelaide,South Australia,Australia
  • 7. School of Pharmacy and Biomedical Science,College of Health,Adelaide University,Adelaide,South Australia,Australia
  • 8. School of Physics,Chemistry & Earth Science,College of Science,Adelaide University,Adelaide,South Australia,Australia
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摘要

关键词

breast cancer/cancer stem cells/chromosome aberrations/mouse model

Key words

breast cancer/cancer stem cells/chromosome aberrations/mouse model

引用本文复制引用

Quy Van-Chanh Le,Zsolt Jurányi,Hien Le,Ivan Kempson,Zsuzsa S.Kocsis,Sisi Liang,Yanrui Li,Briony L.Gliddon,Sheree Bailey,Anh Thai-Quynh Nguyen,Tyron Turnbull,Stuart M.Pitson..Characterizing a murine breast cancer mouse model reveals chromosomal abnormalities in structure and number of single-cell clones and the presence of rare cancer stem cell-like phenotypes[J].动物模型与实验医学(英文),2026,9(2):367-377,11.

基金项目

National Research,Development and Innovation Fund of the Ministry of Culture and Innovation under the National Laboratories Program(National Tumor Biology Laboratory,Grant/Award Number:2022-2.1.1-NL-2022-00010 ()

Senior Research Fellowship from National Health and Medical Research Council of Australia,Grant/Award Number:1156693 ()

Hungarian Thematic Excellence Program,Grant/Award Number:TKP2021-EGA-44 ()

Tour de Cure,Pioneering Grant,Grant/Award Number:RSP-253-18/19 ()

动物模型与实验医学(英文)

2096-5451

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