国医论坛2026，Vol.41Issue(1)：42-45,4.
葶苈大枣泻肺汤加减联合阿奇霉素治疗儿童肺炎支原体肺炎痰热闭肺证疗效观察
Observation on the Efficacy of Tingli Dazao Xiefei Decoction Combined with Azithromycin in Treating Children with Mycoplasma Pneumoniae Pneumonia with Phlegm-Heat Blocking the Lung Syndrome
摘要
Abstract
Objective:To observe the clinical efficacy of Tingli Dazao Xiefei Decoction combined with azithromy-cin in the treatment of Mycoplasma Pneumoniae Pneumonia(MPP)in children with phlegm-heat blocking the lung syndrome.Methods:A retrospective study was conducted on 52 children with MPP who received Tingli Dazao Xiefei Decoction combined with azithromycin treatment at Zhengzhou First People's Hospital from October 2022 to December 2024.Propensity matching scoring method was used to select 52 children with MPP who only received azithromycin treatment as the control group.After 7 days of treatment,the two groupswere compared in terms of clinical efficacy,lung function[forced expiratory volume in one second(FEV1),forced vital capacity(FVC),FEV1/FVC],and inflammatory factors[interleukin-6(IL-6),interleukin-8(IL-8),C-reac-tive protein(CRP)]levels.Results:After treatment,the total clinical efficacy rate in the combined group was 96.15％(42/52),which was higher than that in the control group[82.69％(43/52)](P＜0.05).Both groups showed increased FEV1,FVC,and FEV1/FVC compared to pretreatment(P＜0.05),and the combined group had higher values than the control group(P＜0.05).Both groups showed decreased levels of IL-6,IL-8 and CRP compared to pretreatment(P＜0.05),and the combined group had lower levels than the control group(P＜0.05).Conclusion:The combination of Tingli Dazao Xiefei Decoction and azithromycin in the treat-ment of MPP with phlegm-heat blocking the lung syndrome can improve clinical efficacy by improving lung function and reducing inflammatory factor levels.关键词
肺炎支原体肺炎/葶苈大枣泻肺汤/阿奇霉素/痰热闭肺证/中西医结合疗法Key words
Mycoplasma pneumoniae pneumonia/Tingli Dazao Xiefei Decoction/Azithromycin/Phlegm-heat blocking lung syndrome/Integrated traditional Chinese and Western medicine therapy分类
医药卫生引用本文复制引用
何雷锋,常青,庞二召..葶苈大枣泻肺汤加减联合阿奇霉素治疗儿童肺炎支原体肺炎痰热闭肺证疗效观察[J].国医论坛,2026,41(1):42-45,4.基金项目
河南省医学科技攻关计划(联合共建)项目(LHGJ20190995) （联合共建）
2024年度郑州市医疗卫生领域科技创新指导计划项目(2024YLZDJH121). （2024YLZDJH121）
