国医论坛2026，Vol.41Issue(2)：31-35,5.
桃红四物汤加味佐治创伤性小腿皮肤严重缺损疗效观察
Observation on the Efficacy of Modified Taohong Siwu Decoction as Adjuvant Therapy for Severe Traumatic Skin Defects of the Lower Leg
摘要
Abstract
Objective To observe the clinical efficacy of modified Taohong Siwu Decoction combined with free flap repair in the treatment of severe traumatic skin defects in the lower leg.Methods Sixty-eight patients with severe traumatic skin defects in the lower leg admitted to Jiaozuo Second People's Hospital from November 2022 to May 2025 were selected as study subjects and divided into a treatment group and a control group,with 34 pa-tients in each group,according to a random number table method.The control group was treated with free flap repair,while the treatment group received modified Taohong Siwu Decoction on top of the control group's treat-ment.After 4 weeks of treatment,the survival rate of the skin flaps,incidence of flap vascular crisis,visual ana-log scale(VAS)scores,Short Form-36 Health Survey(SF-36)scores,American Orthopedic Foot and Ankle Society(AOFAS)lower leg-foot function scores,levels of inflammatory markers(WBC,CRP,PCT),wound healing time,and postoperative hospital stay were compared between the two groups.Results After treatment,the survival rate of the skin flaps in the treatment group was 97.06％(32/34),which was higher than that in the control group[82.35％(28/34)(P＜0.05)].The incidence of flap vascular crisis in the treatment group was 5.88％(2/34),which was lower than that in the control group[23.53％(8/34))(P＜0.05)].Both VAS scores decreased after treatment compared to before treatment(P＜0.05),and both SF-36 and AOFAS scores increased after treatment compared to before treatment(P＜0.05),with the improvement being more pro-nounced in the treatment group than in the control group(P＜0.05).WBC,CRP,and PCT levels decreased in both groups,with lower levels in the treatment group than in the control group(P＜0.05).The wound healing time and postoperative hospital stay were shorter in the treatment group than in the control group(P＜0.05).Conclusion Modified Taohong Siwu Decoction combined with free flap repair can improve patient limb function and quality of life by increasing the survival rate of skin flaps,reducing the incidence of vascular crisis,inhibi-ting inflammatory reactions,alleviating pain,and shortening wound healing time in the treatment of severe trau-matic skin defects in the lower leg.关键词
桃红四物汤/游离皮瓣修复术/创伤性小腿皮肤严重缺损/中西医结合疗法Key words
Taohong siwu decoction/Free flap repair/Severe traumatic skin defect of the lower leg/Integrated chinese and western medicine therapy分类
医药卫生引用本文复制引用
石战军,白传光,张豪..桃红四物汤加味佐治创伤性小腿皮肤严重缺损疗效观察[J].国医论坛,2026,41(2):31-35,5.基金项目
河南省中医药科学研究专项课题(2024ZY3070). （2024ZY3070）
