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TGF-β/BMP signaling in skeletal biology:molecular mechanisms,regulatory networks,and therapeutic implications in development,regeneration,and disease

Junguang Liao Nenghua Zhang Haidong Wang Guiqian Chen Taofen Wu Qi Zhang Panpan Shen Ziyi Huang Jiaqi Wang Pengxiang Zhang Sisi Lin Jiashun Pi

骨研究（英文版）2026，Vol.14Issue(1)：109-140,32.

骨研究（英文版）2026，Vol.14Issue(1)：109-140,32.DOI:10.1038/s41413-025-00497-y

TGF-β/BMP signaling in skeletal biology:molecular mechanisms,regulatory networks,and therapeutic implications in development,regeneration,and disease

Junguang Liao ¹Nenghua Zhang ²Haidong Wang ³Guiqian Chen ¹Taofen Wu ⁴Qi Zhang ¹Panpan Shen ¹Ziyi Huang ¹Jiaqi Wang ¹Pengxiang Zhang ¹Sisi Lin ¹Jiashun Pi¹

作者信息

1. Department of Biopharmaceutics,Zhejiang Provincial Engineering Research Center of New Technologies and Applications for Targeted Therapy of Major Diseases,College of Life Science and Medicine,Zhejiang Sci-Tech University,Hangzhou,China
2. Department of Orthopedic Surgery,Jiaxing Traditional Chinese Medicine Hospital,Jiaxing,China
3. Clinical Center,Jiaxing Traditional Chinese Medicine Hospital,Jiaxing,China
4. R&D Department,Ceva Animal Health Technology(Hangzhou)Co.Ltd,Hangzhou,China
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摘要

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Junguang Liao,Nenghua Zhang,Haidong Wang,Guiqian Chen,Taofen Wu,Qi Zhang,Panpan Shen,Ziyi Huang,Jiaqi Wang,Pengxiang Zhang,Sisi Lin,Jiashun Pi..TGF-β/BMP signaling in skeletal biology:molecular mechanisms,regulatory networks,and therapeutic implications in development,regeneration,and disease[J].骨研究（英文版）,2026,14(1):109-140,32.

基金项目

This work was supported by grants by National Natural Science Foundation of China(No.82571024,No.81400489),Zhejiang Provincial Natural Science Foundation of China(LZ23H140001,LTGY23H200006,LGC22H200012),Zhejiang Qianjiang Talent Program(21040040-E),the Fundamental Research Funds of Zhejiang Sci-Tech University(2021Q031),Zhejiang Jiaxing Science Technology Foundation(2023AZ31004,2023AY11045,2023AY31012,2020AY10001),Zhejiang Drug&Health Foundation(2022507032,2023KY340).The authors apologize to the many researchers whose work could not be cited due to space limitations. （No.82571024,No.81400489）

骨研究（英文版）

ISSN：2095-4700

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