寒旱农业科学2026，Vol.5Issue(2)：130-135,6.DOI:10.3969/j.issn.2097-2172.2026.02.006
绵羊PID1基因的生物信息学分析
Bioinformatics Analysis of Sheep PID1 Gene
摘要
Abstract
Phosphotyrosine-interacting structural domain 1(PID1)is a novel gene identified in retroperitoneal adipose tissue of obese individuals,which plays a key regulatory role in the proliferation and differentiation stages of adipocytogenesis.To investigate the function of the sheep PID1 gene,the structural features of the sheep PID1 gene and its encoded product were analysed in this study using bioinformatics software.Results showed that the sheep PID1 gene contains an open reading frame with a maximum length of 612 bp and is thought to encode 203 amino acid residues.The molecular formula of the sheep PID1 protein isC1021H1606N280O304S14,the molecular mass is 23115.36 Da and the theoretical pI is 6.25.By predicting the conditions for the transmembrane region and sig-nal peptide,the results showed that the protein has no transmembrane region and signal peptide and is therefore an unstable hydrophil-ic non-transmembrane protein.These findings provide a theoretical basis for understanding the biological function of the sheep PID1 gene and its role in the regulation of lipid metabolism,which is of great importance for molecular breeding and lipid metabolism re-search in sheep.关键词
绵羊/PID1基因/生物信息学分析Key words
Ovis aries/PID1 gene/Bioinformatics analysis分类
农业科技引用本文复制引用
张蕴,赵之功,马新芳,张小雪..绵羊PID1基因的生物信息学分析[J].寒旱农业科学,2026,5(2):130-135,6.基金项目
甘肃农业大学大学生创新创业训练计划项目(202404032). （202404032）
