中国当代医药2026，Vol.33Issue(5)：79-83,88,6.DOI:10.3969/j.issn.1674-4721.2026.05.16
清瘟败毒饮在热毒蕴结型上尿路结石梗阻致尿源性脓毒血症患者术后的应用效果
Effect of Qingwen Baidu Decoction in postoperative management of urosepsis patients with up per urinary tract stone obstruction and heat-toxin accumulation syndrome
摘要
Abstract
Objective To explore the effect of Qingwen Baidu Decoction in postoperative management of urosepsis patients with upper urinary tract stone obstruction and heat-toxin accumulation syndrome.Methods A total of 60 patients with urosepsis caused by heat-toxin accumulation syndrome upper urinary tract stone obstruction who met the criteria and were admitted to the Department of Urology,Jinjiang Hospital of Traditional Chinese Medicine,Fujian University of Traditional Chinese Medicine from July 2024 to May 2025 were selected as the study subjects,and they were divided into the treatment group(30 cases)and the control group(30 cases)by random number table method.The control group was given antibiotics to fight infection,symptomatic treatment,and vital signs were monitored after surgery,while the treatment group took Qingwen Baidu Decoction on the basis of the control group.The traditional Chinese medicine syndrome scores,acute physiology and chronic health evaluationⅡ(APACHE Ⅱ)scores,white blood cell(WBC)counts,procalcitonin(PCT)and C-reactive pro-tein(CRP)levels,as well as therapeutic efficacy were compared between the two groups.Results There were no statistically significant differences in traditional Chinese medicine syndrome scores,APACHEⅡscores,WBC,CRP,or PCT levels be-tween the two patient groups before treatment(P＞0.05).After treatment,the traditional Chinese medicine syndrome score,APACHEⅡscore,and the levels of WBC,CRP,and PCT in the treatment group were lower than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Qingwen Baidu Decoction can significantly improve symptoms,inhibit inflammatory response,shorten the course of the disease,and promote recovery in patients with urosepsis caused by upper urinary tract stone obstruction caused by heat-toxin accumulation type.关键词
清瘟败毒饮/热毒蕴结证/尿源性脓毒血症/上尿路结石梗阻/临床疗效Key words
Qingwen Baidu Decoction/Heat-toxin accumlation syndrome/Urosepsis/Obstruction of upper urinary tract stones/Clinical efficacy分类
医药卫生引用本文复制引用
许昭亭,洪志坚,颜锡欣..清瘟败毒饮在热毒蕴结型上尿路结石梗阻致尿源性脓毒血症患者术后的应用效果[J].中国当代医药,2026,33(5):79-83,88,6.基金项目
福建中医药大学校管科研课题(XB2024173). （XB2024173）
