吉林中医药2026，Vol.46Issue(3)：274-278,5.DOI:10.13463/j.cnki.jlzyy.2026.03.003
基于"因加而发"探讨慢性萎缩性胃炎"炎癌转化"病机与防治
Pathogenesis and prevention of inflammation-to-cancer transformation in chronic atrophic gastritis based on the theory of"exacerbation due to additional pathogenic factors"
摘要
Abstract
Chronic atrophic gastritis(CAG)is a common gastrointestinal disorder characterized by insidious onset,complex pathogeneses,and a tendency to be difficult to treat.The dynamic pathological progression of"superficial gastritis--atrophic gastritis--intestinal metaplasia--intraepithelial neoplasia--gastric cancer"represents the process of"inflammation-to-cancer transformation"in the stomach.The theory"exacerbation due to additional pathogenic factors"recorded in the Inner Canon of Yellow Emperor is one of the common pathogeneses by which diseases occur in the human body.It refers to the fact that the potential pathogenic factors in the body are suppressed by the body's healthy qi and the person does not get sick.However,these latent factors remain present in the body.When the body is then exposed to new pathogenic factors,the combination of these old and new factors overwhelms the body's healthy qi,which is no longer able to contain the pathogens,leading to the onset of diseases.This view that both old and new pathogenic factors jointly disturb the body and cause it to lose its original state of balance,leading to the development of diseases,is consistent with the pathological progression of inflammation-to-cancer transformation in CAG.Exploring the pathogenesis of CAG's inflammation-to-cancer transformation based on the"exacerbation due to additional pathogenic factors"theory provides an important guidance for delaying or even reversing the progression of CAG to gastric cancer.关键词
慢性萎缩性胃炎/炎癌转化/因加而发/防治Key words
chronic atrophic gastritis/inflammation-to-cancer transformation/exacerbation due to additional pathogenic factors/prevention and control分类
医药卫生引用本文复制引用
曹雨茜,赵一帆,陈鸿鑫,王子硕,姜欣宜,朱磊,沈洪..基于"因加而发"探讨慢性萎缩性胃炎"炎癌转化"病机与防治[J].吉林中医药,2026,46(3):274-278,5.基金项目
国家中医药管理局高水平中医药重点学科项目(中医脾胃病学)(国中医药人教函[2023]85号) （中医脾胃病学）
全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号) （国中医药人教函[2022]75号）
