皮肤性病诊疗学杂志2026，Vol.33Issue(2)：138-141,4.DOI:10.3969/j.issn.1674-8468.2026.02.009
臀部恶性单纯性汗腺棘皮瘤1例
A case of malignant hidroacanthoma simplex on the hip
摘要
Abstract
We report a case of malignant hidroacanthoma simplex on the hip.An 85-year-old female presented with a 6-month history of a papule on her left hip.Dermatological examination showed a brown-colored hyperkeratotic plaque measuring 3 cm × 3 cm with irregular margins and visible surface crusts.Histopathological examination revealed marked hyperkeratosis,acanthosis,papillomatosis,and well-circumscribed intraepidermal tumor nests.Atypical cells with large,hy-perchromatic nuclei and mitotic activity were observed within the tumor nests.Immunohistochemi-cal staining was positive for EMA,CK14,CK20(a few cells),and Cam5.2(a few cells)in the lesional skin.The diagnosis was malignant hidroacanthoma simplex.Complete excision was per-formed,and no recurrence was observed during the 12-month follow-up period.关键词
单纯性汗腺棘皮瘤/恶性Key words
hidroacanthoma simplex/malignant引用本文复制引用
何丽霞,刘迎红,翁立强,龙琴琴,陈柏叡..臀部恶性单纯性汗腺棘皮瘤1例[J].皮肤性病诊疗学杂志,2026,33(2):138-141,4.基金项目
福州市卫生健康中青年人才科研项目(2022-S-rc3) （2022-S-rc3）
