临床口腔医学杂志2026，Vol.42Issue(3)：163-168,6.DOI:10.3969/j.issn.1003-1634.2026.03.009
老年2型糖尿病合并牙健康患者肌少症的患病率及牙健康保护作用分析
Prevalence of sarcopenia and the protective effect of dental health in elderly patients with type 2 diabetes:An a-nalysis
曹国良 1施惠华 1朱珠 1杜岑 1汪海娅1
作者信息
- 1. 上海交通大学医学院附属第九人民医院老年科 上海 201900
- 折叠
摘要
Abstract
Objective:To investigate the association between oral health status and sarcopenia prevalence in elderly patients with type 2 diabetes mellitus(T2DM),analyze the independent protective effect of oral health and its core dimen-sions,and explore its synergistic effects with exercise and nutrition.Methods:A retrospective study was conducted on 402 elderly T2DM patients from January 2020 to December 2024,divided into an oral health group(n=148)and an oral unhealthy group(n=254)based on oral health status.Oral health was defined as no permanent tooth loss,periodontal health(CPI<3),normal occlusal function,and no active caries.Sarcopenia was diagnosed according to AWGS 2019 criteria.Sarcopenia preva-lence and related indicators were compared between the two groups.Multivariate logistic regression was used to analyze the independent protective effect of oral health and its interaction with exercise and nutrition.Results:The overall prevalence of sarcopenia in elderly T2DM patients was 34.6%.The sarcopenia prevalence in the oral health group(19.6%)was significant-ly lower than that in the oral unhealthy group(43.3%,P<0.001).Multivariate regression showed that oral health(OR=0.421),periodontal health(OR=0.455),and normal occlusion(OR=0.510)were independent protective factors against sar-copenia.A significant synergistic protective effect was observed between oral health and exercise≥3 times per week(interac-tion OR=0.300,P<0.001).Oral health had the strongest protective effect on muscle mass reduction(OR=0.386),followed by grip strength decline(OR=0.492)and gait speed reduction(OR=0.618).Conclusion:Elderly T2DM patients with good oral health have a significantly lower prevalence of sarcopenia.Periodontal health and occlusal function are core protective di-mensions against sarcopenia and exhibit synergistic effects with exercise intervention.Clinical management should emphasize oral health maintenance,combined with exercise and nutritional support,to establish an integrated"oral-metabolic-muscle"prevention strategy.关键词
2型糖尿病/老年/牙健康/肌少症/牙周健康/咬合功能Key words
Type 2 diabetes/Elderly/Oral health/Sarcopenia/Periodontal health/Occlusal function分类
医药卫生引用本文复制引用
曹国良,施惠华,朱珠,杜岑,汪海娅..老年2型糖尿病合并牙健康患者肌少症的患病率及牙健康保护作用分析[J].临床口腔医学杂志,2026,42(3):163-168,6.
