畜牧与饲料科学2026,Vol.47Issue(1):1-8,8.DOI:10.12160/j.issn.1672-5190.2026.01.001
肠道微生物通过"肠-肌轴"引起畜禽肌肉代谢异常的机制及其应用策略
Mechanisms and Application Strategies of Gut Microbiota-Induced Muscle Metabolic Abnormalities in Livestock and Poultry via the Gut-Muscle Axis
摘要
Abstract
Gut microbiota not only participate in the digestion and absorption of exogenous nutrients but also regulate protein synthesis and degradation,energy metabolism,and inflammatory responses through the synthesis of metabolites such as short-chain fatty acids and bile acids,thereby being deeply involved in muscle metabolic processes.Based on these findings,scholars have proposed a bidirectional communication mechanism known as the gut-muscle axis.In recent years,with the rapid increase in livestock and poultry production efficiency,muscle metabolic disorders in livestock and poultry have occurred frequently and are closely associated with gut microbiota dysbiosis and its metabolite-mediated inflammatory activation and intestinal barrier damage.This review systematically summarizes the mechanisms by which gut microbiota affect muscle metabolic abnormalities in livestock and poultry via the gut-muscle axis,with emphasis on the processes by which gut microbial metabolites affect meat quality by regulating immune pathways and intestinal barrier functions.Combined with specific cases,such as wooden breast meat and white striping meat,it analyzes the role of the gut-muscle axis in the progression of metabolic abnormalities.Furthermore,the species-specific regulatory characteristics of the gut-muscle axis in pigs,poultry,and ruminants are summarized,alongside its application strategies in livestock and poultry production.This review aims to deepen the understanding of the role played by gut microbiota in muscle metabolic abnormalities,providing a reference for improving muscle health and enhancing meat yield and meat quality via the gut-muscle axis.关键词
肠道微生物/肠-肌轴/畜禽肌肉/肌肉代谢异常/作用机制/畜禽生产Key words
gut microbiota/gut-muscle axis/livestock and poultry muscle/muscle metabolic abnormalities/mechanism of action/livestock and poultry production分类
农业科技引用本文复制引用
黄榆智,何航,黄禹璐,徐兰梦,燕晴,苏少锋,章杰..肠道微生物通过"肠-肌轴"引起畜禽肌肉代谢异常的机制及其应用策略[J].畜牧与饲料科学,2026,47(1):1-8,8.基金项目
重庆市教委科研项目(KJQN202503523) (KJQN202503523)
国家自然科学基金地区科学基金项目(32460830). (32460830)