畜牧与饲料科学2026，Vol.47Issue(1)：72-82,11.DOI:10.12160/j.issn.1672-5190.2026.01.010
选择信号分析在家马驯化与选育性状候选基因挖掘中的应用研究进展
Research Progress on the Application of Selection Signature Analysis in Candidate Gene Mining for Domestication and Breeding Traits of Domestic Horses
摘要
Abstract
Selection signature analysis,as a core analytical approach in population genomics,can identify genomic regions subjected to positive,negative,and balancing selection during long-term natural selection and artificial breeding,providing molecular evidence to elucidate the mechanisms of adaptive evolution and the genetic basis of key traits in animals.This review systematically summarizes the research progress on selection signatures related to important economic and phenotypic traits in domestic horses during domestication and artificial breeding,covering core breeding traits such as body size,athletic performance,and coat color,and also summarizes the characteristics of selection signatures associated with pathological traits retained due to linkage drag.By summarizing the application of selection signature detection techniques and candidate gene screening strategies across diverse horse populations,this review elucidates the pivotal role of this method in revealing population genetic structure,domestication-adaptation mechanisms,and the molecular regulatory mechanisms of economic traits.Finally,in combination with the trends of multi-omics integration and technological development,the review discusses the application prospects of selection signature analysis in equine genomics research,breed improvement,and genetic resource conservation,providing a reference for future molecular breeding and evolutionary studies of domestic horses.关键词
家马/选择信号分析/全基因组重测序/群体基因组/候选基因Key words
domestic horse/selection signature analysis/whole-genome resequencing/population genomics/candidate genes分类
农业科技引用本文复制引用
李文博,图格琴,安塔娜,芒来..选择信号分析在家马驯化与选育性状候选基因挖掘中的应用研究进展[J].畜牧与饲料科学,2026,47(1):72-82,11.基金项目
国家自然科学联合基金重点支持项目(U23A20224). （U23A20224）
