陕西中医2026，Vol.47Issue(3)：350-354,5.DOI:10.3969/j.issn.1000-7369.2026.03.011
息风止动方联合高频重复经颅磁刺激治疗小儿抽动症疗效观察
Efficacy of Xifeng Zhidong formula combined with high-frequency repetitive transcranial magnetic stimulation in treating children with Tourette syndrome
摘要
Abstract
Objective:To observe the efficacy of Xifeng Zhidong formula combined with high-frequency repeti-tive transcranial magnetic stimulation(rTMS)in treating children with Tourette syndrome(TS).Methods:One hun-dred children with TS were selected and grouped using a random number table.All children received conventional psychotherapy and behavioral guidance.The control group was additionally treated with high-frequency rTMS,while the combination group was additionally treated with Xifeng Zhidong formula based on the control group's treatment.Both groups underwent continuous treatment for 4 weeks as one course.The two groups were compared on tradition-al Chinese medicine syndrome scores,inflammatory indicators[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)],Yale Global Tic Severity Scale(YGTSS)scores and Pediatric Quality of Life Inventory(PedsQL)scores before and after treatment,efficacy,and adverse reactions.Results:The combination group reported a total effective rate of 96.00％after treatment,notably higher than that reported by the control group(82.00％)(P＜0.05).The combi-nation group had notably lower traditional Chinese medicine syndrome scores than the control group after treatment(P＜0.05).Compared to the control group,the combination group exhibited notably lower levels of IL-6 and TNF-αafter treatment(P＜0.05).The combination group got notably lower YGTSS scores and notably higher PedsQL scores after treatment(P＜0.05).The overall incidence of adverse reactions did not differ notably between the groups(P＞0.05).Conclusion:Applying Xifeng Zhidong formula combined with high-frequency rTMS to treat chil-dren with TS can effectively improve traditional Chinese medicine syndromes,alleviate inflammation,and enhance the quality of life,with good safety.关键词
小儿抽动症/息风止动方/重复经颅磁刺激/中医证候积分/炎症/白介素-6/肿瘤坏死因子-αKey words
Tourette syndrome/Xifeng Zhidong formula/Repetitive transcranial magnetic stimulation/Tradi-tional Chinese medicine syndrome score/Inflammation/Interleukin-6/Tumor necrosis factor-α分类
医药卫生引用本文复制引用
邢子超,张云沛,王蕊..息风止动方联合高频重复经颅磁刺激治疗小儿抽动症疗效观察[J].陕西中医,2026,47(3):350-354,5.基金项目
河北省中医药管理局科研计划项目(2026414) （2026414）
