陕西中医2026，Vol.47Issue(3)：375-378,4.DOI:10.3969/j.issn.1000-7369.2026.03.016
基于"炎癌转化"理论探讨NETs与肺癌转移的关系
Exploring the relationship between NETs and lung cancer metastasis based on the"inflammation-cancer transformation"theory
摘要
Abstract
Lung cancer,as a public health issue affecting modern society and individual health,is closely associ-ated with the presence of inflammation in its development and progression.According to traditional Chinese medicine theory,"deficiency of the body's defensive energy and accumulation of toxins"is the key pathogenic mechanism un-derlying the occurrence and development of lung cancer.The continuous accumulation of toxins ultimately promotes the"inflammation-to-cancer"transformation and is closely related to lung cancer metastasis.Multiple studies have shown that neutrophil extracellular traps(NETs)interact with cancer cells,with NETs enhancing inflammatory re-sponses and accelerating the inflammation-to-cancer transformation.Based on this,we propose the"inflammation-to-cancer transformation-abnormal NET release-lung cancer metastasis"etiological and pathomechanical perspective,of-fering new insights for clinical treatment.关键词
炎癌转化/中性粒细胞胞外诱捕网/肺癌转移/炎症反应/正虚毒结/发生机制Key words
Inflammatory and cancer transformation/Neutrophil extracellular trap/Lung cancer metastasis/inflammatory response/Deficiency of vital qi(Zheng Xu)and toxin accumulation/Pathogenesis分类
医药卫生引用本文复制引用
邓倩瑜,姚菲,石玮,董福嫱,李宛津,李春姗..基于"炎癌转化"理论探讨NETs与肺癌转移的关系[J].陕西中医,2026,47(3):375-378,4.基金项目
国家自然科学基金资助地区项目(82260956) （82260956）
广西自然科学基金资助面上项目(2025GXNSFAA069458) （2025GXNSFAA069458）
广西中医药大学博士科研启动基金资助项目(2023BS037) （2023BS037）
