饲料工业2026，Vol.47Issue(6)：34-42,9.DOI:10.13302/j.cnki.fi.2026.06.005
Nrf2/NF-κB通路及低氧环境下探讨动物氧化应激的研究进展
Nrf2/NF-κB Pathway and Low Oxygen Environment to Explore Progress of Oxidative Stress in Animals
摘要
Abstract
Oxygen is one of the indispensable elements of the body's life activities.Hypoxia and other fac-tors can induce the increase of reactive oxygen species(ROS)and free radical release in the body,thus breaking the normal oxygen metabolism balance and causing the disorder of lipid metabolism in cell mem-brane.Under hypoxia conditions,the body will produce a non-specific reaction,that is,oxidative stress(OS),which will make the homeostasis of the body unbalanced and eventually lead to local or systemic changes.Nrf2/NF-κB is an important signaling pathway involved in oxidative stress in animals,and the acti-vation and inhibition of its activity play a crucial role in the progression of oxidative stress in animals.There-fore,the mechanism of Nrf2/NF-κB pathway on oxidative stress in animals and the research progress of alle-viating oxidative stress in animals during production and adaptation under yhpoxic environments,which will provide a theoretical basis for future research on reducing stress damage.关键词
氧化应激/Nrf2通路/NF-κB通路/低氧适应性/炎症损伤Key words
oxidative stress/Nrf2 pathway/NF-κB pathway/hypoxic adaptation/inflammatory damage分类
农业科技引用本文复制引用
许恩榕,吴华,陈林,郑润韬,王文胜,刘嘉逸,陈自鑫..Nrf2/NF-κB通路及低氧环境下探讨动物氧化应激的研究进展[J].饲料工业,2026,47(6):34-42,9.基金项目
国家自然科学基金项目[3216200263] （）
