饲料工业2026，Vol.47Issue(6)：96-105,10.DOI:10.13302/j.cnki.fi.2026.06.013
复方中草药对西杂母牛生长性能、血清学指标、免疫功能和肠道菌群的影响
Effects of Compound Chinese Herbal Medicine on Growth Performance,Serological Indicator,Immunity Function and Gut Microbiota in Simmental Crossbred Cattle
摘要
Abstract
This study aimed to investing ate the effects of compound Chinese herbal medicine on growth per-formance,serology indicator,immunity function and gut microbiota in Simmental crossbred cattle.A single-factor randomized trial design was used.Twenty healthy 12-month-old Simmental cross-bred cattle were selected and randomly divided into A and B groups.Each group had 10 replicates.Group A was supplemented with 100 g/(head·d)of compound Chinese herbal medicine in the basal diet,while group B was fed the basal diet alone.The pre-trial period was 5 d,and the was 90 d.Growth performance,serological indicator,and gut microbiota abundance were measured on day 30,60,and 90 of the formal trial period.The results showed that:① the average daily gain of group A was increased by 0.04 kg(P<0.05),0.15 kg(P<0.01),and 0.15 kg(P<0.01)compared with group B on day 30,60,and 90,respectively.② Compared with group B,the contents of alanine aminotransferase(ALT)and cre-atinine(CREA)in group A were significantly lower(P<0.01),and the albumin(ALB)content was signifi-cantly higher(P<0.01)on day 30.The contents of direct bilirubin(DBIL)and total bile acid(TBA)in group A were significantly lower than group B(P<0.05).The γ-glutamyl transferase(γ-GT)activity was signifi-cantly lower in group A than in group B on day 30 and 60(P<0.05).③ The serum contents of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),and interleukin-10(IL-10)in group A were lower than those in group B(P>0.05).④ With the increase in trial duration,the number of gut microbiota OTUs in group A gradually increased,which was different from group B.At the phylum level,the dominant phyla in both groups were Firmicutes and Bacteroidetes.At the family level,on day 30,the relative abundances of Pre-votellaceae(P=0.001)and Monoglobaceae(P=0.03)in group A were significantly(P<0.01)or extremely sig-nificantly lower(P<0.05)than those in group B,while the relative abundance of Christensenellaceae was extremely significantly higher(P=0.009).On day 60,the relative abundance of Prevotellaceae in group A was significantly lower than that in group B(P=0.042).In the alpha diversity analysis,the Simpson index of group A was extremely significantly higher than that of group B on day 30(P=0.008),while no significant dif-ferences were observed in other indices(P>0.05).To sum up,compound Chinese herbal medicine could sig-nificantly improve the growth performance of Simmental crossbred cattle.It also improved liver and kidney function,enhanced immunity function,promoted the proliferation of Christensenellaceae in the gut micro-biota,and inhibited the colonization of the conditional pathogen Prevotellaceae.Short-term feeding could improve the structure of the gut microbiota and promote long-term healthy growth.关键词
复方中草药/西杂母牛/血清学指标/免疫功能/肠道菌群Key words
compound Chinese herbal medicine/Simmental crossbred cattle/serological indicator/immu-nity function/gut microbiota分类
农业科技引用本文复制引用
李文,樊新丽,况玲,罗生金..复方中草药对西杂母牛生长性能、血清学指标、免疫功能和肠道菌群的影响[J].饲料工业,2026,47(6):96-105,10.基金项目
新疆"天山英才"培养计划青年科技拔尖人才项目[2022TSYCJC0024] （）
哈密市科技人才领跑工程项目[2024hmkjqnbj02] （）
哈密市科学研究与技术开发项目[hmskjj-hxm202425] （）
