首页|期刊导航|生物设计研究（英文）|Identification and engineering of a UDP-rhamnosyltransferase from Trillium tschonoskii for heterologous biosynthesis of polyphyllin Ⅱ in yeast

Identification and engineering of a UDP-rhamnosyltransferase from Trillium tschonoskii for heterologous biosynthesis of polyphyllin Ⅱ in yeast

Yuxin Yang Yating Hu Xianan Zhang Haowen Wang Ziya Wu Xing Wang Yuru Tong Wei Huang Xuan Liu Huan Zhao Juan Guo

生物设计研究（英文）2025，Vol.7Issue(4)：20-30,11.

生物设计研究（英文）2025，Vol.7Issue(4)：20-30,11.DOI:10.1016/j.bidere.2025.100047

Identification and engineering of a UDP-rhamnosyltransferase from Trillium tschonoskii for heterologous biosynthesis of polyphyllin Ⅱ in yeast

Yuxin Yang ¹Yating Hu ²Xianan Zhang ¹Haowen Wang ¹Ziya Wu ¹Xing Wang ¹Yuru Tong ³Wei Huang ⁴Xuan Liu ¹Huan Zhao ¹Juan Guo²

作者信息

1. School of Traditional Chinese Medicine,Capital Medical University,Beijing,100069,China
2. National Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing,100700,China
3. School of Pharmaceutical Science,Capital Medical University,Beijing,100069,China
4. School of Pharmaceutical Science,Hubei University of Chinese Medicine,Wuhan,430060,China
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摘要

关键词

Trillium tschonoskii/Rhamnosyltransferase/Protein engineering/Polyphyllin Ⅱ/Biosynthesis

Key words

Trillium tschonoskii/Rhamnosyltransferase/Protein engineering/Polyphyllin Ⅱ/Biosynthesis

引用本文复制引用

Yuxin Yang,Yating Hu,Xianan Zhang,Haowen Wang,Ziya Wu,Xing Wang,Yuru Tong,Wei Huang,Xuan Liu,Huan Zhao,Juan Guo..Identification and engineering of a UDP-rhamnosyltransferase from Trillium tschonoskii for heterologous biosynthesis of polyphyllin Ⅱ in yeast[J].生物设计研究（英文）,2025,7(4):20-30,11.

基金项目

This work was supported by the Beijing Natural Science Foundation(7232264),the Ability Establishment of Sustainable Use for Valuable Chinese Medicine Resources(2060302),the National Natural Science Foundation of China(81974515),and the Central Laboratory of Capital Medical University. （7232264）

生物设计研究（英文）

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