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De novo biosynthesis of Astragalus bioactive isoflavonoid calycosin-7-glucoside in yeast

Cong Chen Tengfei Liu Ying Huang Jiazhang Lian

生物设计研究（英文）2025，Vol.7Issue(4)：39-46,8.

生物设计研究（英文）2025，Vol.7Issue(4)：39-46,8.DOI:10.1016/j.bidere.2025.100058

De novo biosynthesis of Astragalus bioactive isoflavonoid calycosin-7-glucoside in yeast

Cong Chen ¹Tengfei Liu ¹Ying Huang ¹Jiazhang Lian²

作者信息

1. Key Laboratory of Biomass Chemical Engineering of Ministry of Education & State Key Laboratory of Biobased Transportation Fuel Technology,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou,310027,China
2. Key Laboratory of Biomass Chemical Engineering of Ministry of Education & State Key Laboratory of Biobased Transportation Fuel Technology,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou,310027,China||Zhejiang Key Laboratory of Intelligent Manufacturing for Functional Chemicals,ZJU-Hangzhou Global Scientific and Technological Innovation Center,Zhejiang University,Hangzhou,310000,China||State Key Laboratory of Coordination Chemistry,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing,210093,China
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摘要

关键词

Calycosin-7-glucoside/Isoflavonoids/Plant natural products/Yeast/Synthetic biology

Key words

Calycosin-7-glucoside/Isoflavonoids/Plant natural products/Yeast/Synthetic biology

引用本文复制引用

Cong Chen,Tengfei Liu,Ying Huang,Jiazhang Lian..De novo biosynthesis of Astragalus bioactive isoflavonoid calycosin-7-glucoside in yeast[J].生物设计研究（英文）,2025,7(4):39-46,8.

基金项目

This work was financially supported by the National Key Research and Development Program of China(2024YFA0918000),the National Natural Science Foundation of China(22278361 and 22478341),the Fundamental Research Funds for the Central Universities(226-2025-00044),and Open Research Fund of State Key Laboratory of Coordina-tion Chemistry,School of Chemistry and Chemical Engineering,Nanjing University.We would like to thank iBioFoundry and Core Facility at ZJU-Hangzhou Global Scientific and Technological Innovation Center for analytical support. （2024YFA0918000）

生物设计研究（英文）

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